Anti-B3A4/ SLC4A9/ AE4 monoclonal antibody

Anti-B3A4/ SLC4A9/ AE4 antibody for FACS & in-vivo assay

Target products collectionGo to SLC4A9/SLC4A9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1642-Ab-1/ GM-Tg-hg-MP1642-Ab-2Anti-Human SLC4A9 monoclonal antibodyHuman
GM-Tg-rg-MP1642-Ab-1/ GM-Tg-rg-MP1642-Ab-2Anti-Rat SLC4A9 monoclonal antibodyRat
GM-Tg-mg-MP1642-Ab-1/ GM-Tg-mg-MP1642-Ab-2Anti-Mouse SLC4A9 monoclonal antibodyMouse
GM-Tg-cynog-MP1642-Ab-1/ GM-Tg-cynog-MP1642-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC4A9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1642-Ab-1/ GM-Tg-felg-MP1642-Ab-2Anti-Feline SLC4A9 monoclonal antibodyFeline
GM-Tg-cang-MP1642-Ab-1/ GM-Tg-cang-MP1642-Ab-2Anti-Canine SLC4A9 monoclonal antibodyCanine
GM-Tg-bovg-MP1642-Ab-1/ GM-Tg-bovg-MP1642-Ab-2Anti-Bovine SLC4A9 monoclonal antibodyBovine
GM-Tg-equg-MP1642-Ab-1/ GM-Tg-equg-MP1642-Ab-2Anti-Equine SLC4A9 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1642-Ab-1/ GM-Tg-hg-MP1642-Ab-2; GM-Tg-rg-MP1642-Ab-1/ GM-Tg-rg-MP1642-Ab-2;
GM-Tg-mg-MP1642-Ab-1/ GM-Tg-mg-MP1642-Ab-2; GM-Tg-cynog-MP1642-Ab-1/ GM-Tg-cynog-MP1642-Ab-2;
GM-Tg-felg-MP1642-Ab-1/ GM-Tg-felg-MP1642-Ab-2; GM-Tg-cang-MP1642-Ab-1/ GM-Tg-cang-MP1642-Ab-2;
GM-Tg-bovg-MP1642-Ab-1/ GM-Tg-bovg-MP1642-Ab-2; GM-Tg-equg-MP1642-Ab-1/ GM-Tg-equg-MP1642-Ab-2
Products NameAnti-SLC4A9 monoclonal antibody
Formatmab
Target NameSLC4A9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC4A9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species B3A4/ SLC4A9/ AE4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1642
    Target NameSLC4A9
    Gene ID83697,240215,266612,695782,487162,101091500,509031,100072424
    Gene Symbol and SynonymsAE4,D630003B07,D630024F24Rik,SLC4A9
    Uniprot AccessionQ96Q91,Q8K4V2
    Uniprot Entry NameB3A4_HUMAN,B3A4_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000113073
    Target ClassificationN/A

    The target: SLC4A9, gene name: SLC4A9, also named as AE4. The protein encoded by this gene is a membrane protein involved in anion exchange. Expression of this gene is mostly limited to the kidney. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.