Anti-S20A1/ SLC20A1/ GLVR1 monoclonal antibody

Anti-S20A1/ SLC20A1/ GLVR1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC20A1/SLC20A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1553-Ab-1/ GM-Tg-hg-MP1553-Ab-2Anti-Human SLC20A1 monoclonal antibodyHuman
GM-Tg-rg-MP1553-Ab-1/ GM-Tg-rg-MP1553-Ab-2Anti-Rat SLC20A1 monoclonal antibodyRat
GM-Tg-mg-MP1553-Ab-1/ GM-Tg-mg-MP1553-Ab-2Anti-Mouse SLC20A1 monoclonal antibodyMouse
GM-Tg-cynog-MP1553-Ab-1/ GM-Tg-cynog-MP1553-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC20A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1553-Ab-1/ GM-Tg-felg-MP1553-Ab-2Anti-Feline SLC20A1 monoclonal antibodyFeline
GM-Tg-cang-MP1553-Ab-1/ GM-Tg-cang-MP1553-Ab-2Anti-Canine SLC20A1 monoclonal antibodyCanine
GM-Tg-bovg-MP1553-Ab-1/ GM-Tg-bovg-MP1553-Ab-2Anti-Bovine SLC20A1 monoclonal antibodyBovine
GM-Tg-equg-MP1553-Ab-1/ GM-Tg-equg-MP1553-Ab-2Anti-Equine SLC20A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1553-Ab-1/ GM-Tg-hg-MP1553-Ab-2; GM-Tg-rg-MP1553-Ab-1/ GM-Tg-rg-MP1553-Ab-2;
GM-Tg-mg-MP1553-Ab-1/ GM-Tg-mg-MP1553-Ab-2; GM-Tg-cynog-MP1553-Ab-1/ GM-Tg-cynog-MP1553-Ab-2;
GM-Tg-felg-MP1553-Ab-1/ GM-Tg-felg-MP1553-Ab-2; GM-Tg-cang-MP1553-Ab-1/ GM-Tg-cang-MP1553-Ab-2;
GM-Tg-bovg-MP1553-Ab-1/ GM-Tg-bovg-MP1553-Ab-2; GM-Tg-equg-MP1553-Ab-1/ GM-Tg-equg-MP1553-Ab-2
Products NameAnti-SLC20A1 monoclonal antibody
Formatmab
Target NameSLC20A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC20A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S20A1/ SLC20A1/ GLVR1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1553
    Target NameSLC20A1
    Gene ID6574,20515,81826,699462,483066,493789,514255,100064887
    Gene Symbol and SynonymsGlvr-1,GLVR1,PiT-1,PIT1,SLC20A1
    Uniprot AccessionQ8WUM9,Q9JJP0,O97596
    Uniprot Entry NameS20A1_HUMAN,S20A1_RAT,S20A1_FELCA
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000144136
    Target ClassificationN/A

    The target: SLC20A1, gene name: SLC20A1, also named as GLVR1, Glvr-1, PIT1, PiT-1. The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.