Anti-SDC3/ SDCN/ SYND3 monoclonal antibody

Anti-SDC3/ SDCN/ SYND3 antibody for FACS & in-vivo assay

Target products collectionGo to SDC3/SDC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1492-Ab-1/ GM-Tg-hg-MP1492-Ab-2Anti-Human SDC3 monoclonal antibodyHuman
GM-Tg-rg-MP1492-Ab-1/ GM-Tg-rg-MP1492-Ab-2Anti-Rat SDC3 monoclonal antibodyRat
GM-Tg-mg-MP1492-Ab-1/ GM-Tg-mg-MP1492-Ab-2Anti-Mouse SDC3 monoclonal antibodyMouse
GM-Tg-cynog-MP1492-Ab-1/ GM-Tg-cynog-MP1492-Ab-2Anti-Cynomolgus/ Rhesus macaque SDC3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1492-Ab-1/ GM-Tg-felg-MP1492-Ab-2Anti-Feline SDC3 monoclonal antibodyFeline
GM-Tg-cang-MP1492-Ab-1/ GM-Tg-cang-MP1492-Ab-2Anti-Canine SDC3 monoclonal antibodyCanine
GM-Tg-bovg-MP1492-Ab-1/ GM-Tg-bovg-MP1492-Ab-2Anti-Bovine SDC3 monoclonal antibodyBovine
GM-Tg-equg-MP1492-Ab-1/ GM-Tg-equg-MP1492-Ab-2Anti-Equine SDC3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1492-Ab-1/ GM-Tg-hg-MP1492-Ab-2; GM-Tg-rg-MP1492-Ab-1/ GM-Tg-rg-MP1492-Ab-2;
GM-Tg-mg-MP1492-Ab-1/ GM-Tg-mg-MP1492-Ab-2; GM-Tg-cynog-MP1492-Ab-1/ GM-Tg-cynog-MP1492-Ab-2;
GM-Tg-felg-MP1492-Ab-1/ GM-Tg-felg-MP1492-Ab-2; GM-Tg-cang-MP1492-Ab-1/ GM-Tg-cang-MP1492-Ab-2;
GM-Tg-bovg-MP1492-Ab-1/ GM-Tg-bovg-MP1492-Ab-2; GM-Tg-equg-MP1492-Ab-1/ GM-Tg-equg-MP1492-Ab-2
Products NameAnti-SDC3 monoclonal antibody
Formatmab
Target NameSDC3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SDC3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SDC3/ SDCN/ SYND3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1492
    Target NameSDC3
    Gene ID9672,20970,116673,704374,487323,101093121,618198,100070525
    Gene Symbol and SynonymsmKIAA0468,SDC3,SDCN,syn-3,SYND3
    Uniprot AccessionO75056,P33671
    Uniprot Entry NameSDC3_HUMAN,SDC3_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162512
    Target ClassificationN/A

    The target: SDC3, gene name: SDC3, also named as SDCN, SYND3. The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.