Anti-RAB5C/ L1880L/ RAB5L monoclonal antibody

Anti-RAB5C/ L1880L/ RAB5L antibody for FACS & in-vivo assay

Target products collectionGo to RAB5C/RAB5C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1445-Ab-1/ GM-Tg-hg-MP1445-Ab-2Anti-Human RAB5C monoclonal antibodyHuman
GM-Tg-rg-MP1445-Ab-1/ GM-Tg-rg-MP1445-Ab-2Anti-Rat RAB5C monoclonal antibodyRat
GM-Tg-mg-MP1445-Ab-1/ GM-Tg-mg-MP1445-Ab-2Anti-Mouse RAB5C monoclonal antibodyMouse
GM-Tg-cynog-MP1445-Ab-1/ GM-Tg-cynog-MP1445-Ab-2Anti-Cynomolgus/ Rhesus macaque RAB5C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1445-Ab-1/ GM-Tg-felg-MP1445-Ab-2Anti-Feline RAB5C monoclonal antibodyFeline
GM-Tg-cang-MP1445-Ab-1/ GM-Tg-cang-MP1445-Ab-2Anti-Canine RAB5C monoclonal antibodyCanine
GM-Tg-bovg-MP1445-Ab-1/ GM-Tg-bovg-MP1445-Ab-2Anti-Bovine RAB5C monoclonal antibodyBovine
GM-Tg-equg-MP1445-Ab-1/ GM-Tg-equg-MP1445-Ab-2Anti-Equine RAB5C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1445-Ab-1/ GM-Tg-hg-MP1445-Ab-2; GM-Tg-rg-MP1445-Ab-1/ GM-Tg-rg-MP1445-Ab-2;
GM-Tg-mg-MP1445-Ab-1/ GM-Tg-mg-MP1445-Ab-2; GM-Tg-cynog-MP1445-Ab-1/ GM-Tg-cynog-MP1445-Ab-2;
GM-Tg-felg-MP1445-Ab-1/ GM-Tg-felg-MP1445-Ab-2; GM-Tg-cang-MP1445-Ab-1/ GM-Tg-cang-MP1445-Ab-2;
GM-Tg-bovg-MP1445-Ab-1/ GM-Tg-bovg-MP1445-Ab-2; GM-Tg-equg-MP1445-Ab-1/ GM-Tg-equg-MP1445-Ab-2
Products NameAnti-RAB5C monoclonal antibody
Formatmab
Target NameRAB5C
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RAB5C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RAB5C/ L1880L/ RAB5L VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1445
    Target NameRAB5C
    Gene ID5878,19345,287709,709308,403941,101094966,613749,100053004
    Gene Symbol and SynonymsL1880,RAB5B,RAB5C,RAB5CL,RAB5L,RABL
    Uniprot AccessionP51148,P51147,Q58DS9
    Uniprot Entry NameRAB5C_HUMAN,RAB5C_CANLF,RAB5C_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000108774
    Target ClassificationN/A

    The target: RAB5C, gene name: RAB5C, also named as L1880L, RAB5L, RABL, RAB5C. Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.