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Anti-PSG9/ PS34/ PSBG-11 monoclonal antibody
Anti-PSG9/ PS34/ PSBG-11 antibody for FACS & in-vivo assay
Go to PSG9/PSG9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1419-Ab-1/ GM-Tg-hg-MP1419-Ab-2 | Anti-Human PSG9 monoclonal antibody | Human |
| GM-Tg-rg-MP1419-Ab-1/ GM-Tg-rg-MP1419-Ab-2 | Anti-Rat PSG9 monoclonal antibody | Rat |
| GM-Tg-mg-MP1419-Ab-1/ GM-Tg-mg-MP1419-Ab-2 | Anti-Mouse PSG9 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1419-Ab-1/ GM-Tg-cynog-MP1419-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PSG9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1419-Ab-1/ GM-Tg-felg-MP1419-Ab-2 | Anti-Feline PSG9 monoclonal antibody | Feline |
| GM-Tg-cang-MP1419-Ab-1/ GM-Tg-cang-MP1419-Ab-2 | Anti-Canine PSG9 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1419-Ab-1/ GM-Tg-bovg-MP1419-Ab-2 | Anti-Bovine PSG9 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1419-Ab-1/ GM-Tg-equg-MP1419-Ab-2 | Anti-Equine PSG9 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1419-Ab-1/ GM-Tg-hg-MP1419-Ab-2; GM-Tg-rg-MP1419-Ab-1/ GM-Tg-rg-MP1419-Ab-2; GM-Tg-mg-MP1419-Ab-1/ GM-Tg-mg-MP1419-Ab-2; GM-Tg-cynog-MP1419-Ab-1/ GM-Tg-cynog-MP1419-Ab-2; GM-Tg-felg-MP1419-Ab-1/ GM-Tg-felg-MP1419-Ab-2; GM-Tg-cang-MP1419-Ab-1/ GM-Tg-cang-MP1419-Ab-2; GM-Tg-bovg-MP1419-Ab-1/ GM-Tg-bovg-MP1419-Ab-2; GM-Tg-equg-MP1419-Ab-1/ GM-Tg-equg-MP1419-Ab-2 |
| Products Name | Anti-PSG9 monoclonal antibody |
| Format | mab |
| Target Name | PSG9 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PSG9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PSG9/ PS34/ PSBG-11 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1419 |
| Target Name | PSG9 |
| Gene ID | 5678 |
| Gene Symbol and Synonyms | PS34,PSBG-11,PSBG-9,PSG11,PSG9,PSGII |
| Uniprot Accession | Q00887 |
| Uniprot Entry Name | PSG9_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000183668 |
| Target Classification | N/A |
The target: PSG9, gene name: PSG9, also named as PS34, PSBG-11, PSBG-9, PSG11, PSGII. The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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