Anti-PRLHR/ GPR10/ GR3 monoclonal antibody

Anti-PRLHR/ GPR10/ GR3 antibody for FACS & in-vivo assay

Target products collectionGo to PRLHR/PRLHR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1404-Ab-1/ GM-Tg-hg-MP1404-Ab-2Anti-Human PRLHR monoclonal antibodyHuman
GM-Tg-rg-MP1404-Ab-1/ GM-Tg-rg-MP1404-Ab-2Anti-Rat PRLHR monoclonal antibodyRat
GM-Tg-mg-MP1404-Ab-1/ GM-Tg-mg-MP1404-Ab-2Anti-Mouse PRLHR monoclonal antibodyMouse
GM-Tg-cynog-MP1404-Ab-1/ GM-Tg-cynog-MP1404-Ab-2Anti-Cynomolgus/ Rhesus macaque PRLHR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1404-Ab-1/ GM-Tg-felg-MP1404-Ab-2Anti-Feline PRLHR monoclonal antibodyFeline
GM-Tg-cang-MP1404-Ab-1/ GM-Tg-cang-MP1404-Ab-2Anti-Canine PRLHR monoclonal antibodyCanine
GM-Tg-bovg-MP1404-Ab-1/ GM-Tg-bovg-MP1404-Ab-2Anti-Bovine PRLHR monoclonal antibodyBovine
GM-Tg-equg-MP1404-Ab-1/ GM-Tg-equg-MP1404-Ab-2Anti-Equine PRLHR monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1404-Ab-1/ GM-Tg-hg-MP1404-Ab-2; GM-Tg-rg-MP1404-Ab-1/ GM-Tg-rg-MP1404-Ab-2;
GM-Tg-mg-MP1404-Ab-1/ GM-Tg-mg-MP1404-Ab-2; GM-Tg-cynog-MP1404-Ab-1/ GM-Tg-cynog-MP1404-Ab-2;
GM-Tg-felg-MP1404-Ab-1/ GM-Tg-felg-MP1404-Ab-2; GM-Tg-cang-MP1404-Ab-1/ GM-Tg-cang-MP1404-Ab-2;
GM-Tg-bovg-MP1404-Ab-1/ GM-Tg-bovg-MP1404-Ab-2; GM-Tg-equg-MP1404-Ab-1/ GM-Tg-equg-MP1404-Ab-2
Products NameAnti-PRLHR monoclonal antibody
Formatmab
Target NamePRLHR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRLHR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PRLHR/ GPR10/ GR3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1404
    Target NamePRLHR
    Gene ID2834,226278,246075,712538,486911,101087527,510397,100066425
    Gene Symbol and SynonymsGm339,GPR10,GR3,PRLHR,PrRPR,Uhr-1
    Uniprot AccessionP49683,Q64121,Q4EW11
    Uniprot Entry NamePRLHR_HUMAN,PRLHR_RAT,PRLHR_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119973
    Target ClassificationGPCR

    The target: PRLHR, gene name: PRLHR, also named as GPR10, GR3, PrRPR. PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.