Anti-OR8I2/ OR11-170 monoclonal antibody

Anti-OR8I2/ OR11-170 antibody for FACS & in-vivo assay

Target products collectionGo to OR8I2/OR8I2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1286-Ab-1/ GM-Tg-hg-MP1286-Ab-2Anti-Human OR8I2 monoclonal antibodyHuman
GM-Tg-rg-MP1286-Ab-1/ GM-Tg-rg-MP1286-Ab-2Anti-Rat OR8I2 monoclonal antibodyRat
GM-Tg-mg-MP1286-Ab-1/ GM-Tg-mg-MP1286-Ab-2Anti-Mouse OR8I2 monoclonal antibodyMouse
GM-Tg-cynog-MP1286-Ab-1/ GM-Tg-cynog-MP1286-Ab-2Anti-Cynomolgus/ Rhesus macaque OR8I2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1286-Ab-1/ GM-Tg-felg-MP1286-Ab-2Anti-Feline OR8I2 monoclonal antibodyFeline
GM-Tg-cang-MP1286-Ab-1/ GM-Tg-cang-MP1286-Ab-2Anti-Canine OR8I2 monoclonal antibodyCanine
GM-Tg-bovg-MP1286-Ab-1/ GM-Tg-bovg-MP1286-Ab-2Anti-Bovine OR8I2 monoclonal antibodyBovine
GM-Tg-equg-MP1286-Ab-1/ GM-Tg-equg-MP1286-Ab-2Anti-Equine OR8I2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1286-Ab-1/ GM-Tg-hg-MP1286-Ab-2; GM-Tg-rg-MP1286-Ab-1/ GM-Tg-rg-MP1286-Ab-2;
GM-Tg-mg-MP1286-Ab-1/ GM-Tg-mg-MP1286-Ab-2; GM-Tg-cynog-MP1286-Ab-1/ GM-Tg-cynog-MP1286-Ab-2;
GM-Tg-felg-MP1286-Ab-1/ GM-Tg-felg-MP1286-Ab-2; GM-Tg-cang-MP1286-Ab-1/ GM-Tg-cang-MP1286-Ab-2;
GM-Tg-bovg-MP1286-Ab-1/ GM-Tg-bovg-MP1286-Ab-2; GM-Tg-equg-MP1286-Ab-1/ GM-Tg-equg-MP1286-Ab-2
Products NameAnti-OR8I2 monoclonal antibody
Formatmab
Target NameOR8I2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OR8I2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OR8I2/ OR11-170 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1286
    Target NameOR8I2
    Gene ID120586,709392,100300545,106781434
    Gene Symbol and SynonymsOR11-170,OR8I2
    Uniprot AccessionQ8N0Y5
    Uniprot Entry NameOR8I2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172154
    Target ClassificationN/A

    The target: OR8I2, gene name: OR8I2, also named as OR11-170. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.