Anti-OPN3/ ECPN/ PPP1R116 monoclonal antibody

Anti-OPN3/ ECPN/ PPP1R116 antibody for FACS & in-vivo assay

Target products collectionGo to OPN3/OPN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0924-Ab-1/ GM-Tg-hg-MP0924-Ab-2Anti-Human OPN3 monoclonal antibodyHuman
GM-Tg-rg-MP0924-Ab-1/ GM-Tg-rg-MP0924-Ab-2Anti-Rat OPN3 monoclonal antibodyRat
GM-Tg-mg-MP0924-Ab-1/ GM-Tg-mg-MP0924-Ab-2Anti-Mouse OPN3 monoclonal antibodyMouse
GM-Tg-cynog-MP0924-Ab-1/ GM-Tg-cynog-MP0924-Ab-2Anti-Cynomolgus/ Rhesus macaque OPN3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0924-Ab-1/ GM-Tg-felg-MP0924-Ab-2Anti-Feline OPN3 monoclonal antibodyFeline
GM-Tg-cang-MP0924-Ab-1/ GM-Tg-cang-MP0924-Ab-2Anti-Canine OPN3 monoclonal antibodyCanine
GM-Tg-bovg-MP0924-Ab-1/ GM-Tg-bovg-MP0924-Ab-2Anti-Bovine OPN3 monoclonal antibodyBovine
GM-Tg-equg-MP0924-Ab-1/ GM-Tg-equg-MP0924-Ab-2Anti-Equine OPN3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0924-Ab-1/ GM-Tg-hg-MP0924-Ab-2; GM-Tg-rg-MP0924-Ab-1/ GM-Tg-rg-MP0924-Ab-2;
GM-Tg-mg-MP0924-Ab-1/ GM-Tg-mg-MP0924-Ab-2; GM-Tg-cynog-MP0924-Ab-1/ GM-Tg-cynog-MP0924-Ab-2;
GM-Tg-felg-MP0924-Ab-1/ GM-Tg-felg-MP0924-Ab-2; GM-Tg-cang-MP0924-Ab-1/ GM-Tg-cang-MP0924-Ab-2;
GM-Tg-bovg-MP0924-Ab-1/ GM-Tg-bovg-MP0924-Ab-2; GM-Tg-equg-MP0924-Ab-1/ GM-Tg-equg-MP0924-Ab-2
Products NameAnti-OPN3 monoclonal antibody
Formatmab
Target NameOPN3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OPN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OPN3/ ECPN/ PPP1R116 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0924
    Target NameOPN3
    Gene ID23596,13603,498289,707436,102155438,101095542,100847752,100060517
    Gene Symbol and SynonymsECPN,ERO,OPN3,opsin-3,PPP1R116
    Uniprot AccessionQ9H1Y3
    Uniprot Entry NameOPN3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000054277
    Target ClassificationN/A

    The target: OPN3, gene name: OPN3, also named as ECPN, PPP1R116. Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.