Anti-NLGN1/ NL1 monoclonal antibody

Anti-NLGN1/ NL1 antibody for FACS & in-vivo assay

Target products collectionGo to NLGN1/NLGN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0886-Ab-1/ GM-Tg-hg-MP0886-Ab-2Anti-Human NLGN1 monoclonal antibodyHuman
GM-Tg-rg-MP0886-Ab-1/ GM-Tg-rg-MP0886-Ab-2Anti-Rat NLGN1 monoclonal antibodyRat
GM-Tg-mg-MP0886-Ab-1/ GM-Tg-mg-MP0886-Ab-2Anti-Mouse NLGN1 monoclonal antibodyMouse
GM-Tg-cynog-MP0886-Ab-1/ GM-Tg-cynog-MP0886-Ab-2Anti-Cynomolgus/ Rhesus macaque NLGN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0886-Ab-1/ GM-Tg-felg-MP0886-Ab-2Anti-Feline NLGN1 monoclonal antibodyFeline
GM-Tg-cang-MP0886-Ab-1/ GM-Tg-cang-MP0886-Ab-2Anti-Canine NLGN1 monoclonal antibodyCanine
GM-Tg-bovg-MP0886-Ab-1/ GM-Tg-bovg-MP0886-Ab-2Anti-Bovine NLGN1 monoclonal antibodyBovine
GM-Tg-equg-MP0886-Ab-1/ GM-Tg-equg-MP0886-Ab-2Anti-Equine NLGN1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0886-Ab-1/ GM-Tg-hg-MP0886-Ab-2; GM-Tg-rg-MP0886-Ab-1/ GM-Tg-rg-MP0886-Ab-2;
GM-Tg-mg-MP0886-Ab-1/ GM-Tg-mg-MP0886-Ab-2; GM-Tg-cynog-MP0886-Ab-1/ GM-Tg-cynog-MP0886-Ab-2;
GM-Tg-felg-MP0886-Ab-1/ GM-Tg-felg-MP0886-Ab-2; GM-Tg-cang-MP0886-Ab-1/ GM-Tg-cang-MP0886-Ab-2;
GM-Tg-bovg-MP0886-Ab-1/ GM-Tg-bovg-MP0886-Ab-2; GM-Tg-equg-MP0886-Ab-1/ GM-Tg-equg-MP0886-Ab-2
Products NameAnti-NLGN1 monoclonal antibody
Formatmab
Target NameNLGN1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NLGN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NLGN1/ NL1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP001975human Nlgn1 Lentivirus particle
    ORF Viral VectorpGMLP001975human Nlgn1 Lentivirus plasmid
    ORF Viral VectorpGMLPm004766mouse Nlgn1 Lentivirus plasmid
    ORF Viral VectorvGMLPm004766mouse Nlgn1 Lentivirus particle


    Target information

    Target IDGM-MP0886
    Target NameNLGN1
    Gene ID22871,192167,116647,693541,488173,101081489,530042,100058013
    Gene Symbol and Synonyms6330415N05Rik,mKIAA1070,NL1,Nlg1,NLGN1
    Uniprot AccessionQ8N2Q7,Q62765
    Uniprot Entry NameNLGN1_HUMAN,NLGN1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169760
    Target ClassificationN/A

    The target: NLGN1, gene name: NLGN1, also named as NL1. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.