Anti-NKAI1/ NKAIN1/ FAM77C monoclonal antibody

Anti-NKAI1/ NKAIN1/ FAM77C antibody for FACS & in-vivo assay

Target products collectionGo to NKAIN1/NKAIN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0880-Ab-1/ GM-Tg-hg-MP0880-Ab-2Anti-Human NKAIN1 monoclonal antibodyHuman
GM-Tg-rg-MP0880-Ab-1/ GM-Tg-rg-MP0880-Ab-2Anti-Rat NKAIN1 monoclonal antibodyRat
GM-Tg-mg-MP0880-Ab-1/ GM-Tg-mg-MP0880-Ab-2Anti-Mouse NKAIN1 monoclonal antibodyMouse
GM-Tg-cynog-MP0880-Ab-1/ GM-Tg-cynog-MP0880-Ab-2Anti-Cynomolgus/ Rhesus macaque NKAIN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0880-Ab-1/ GM-Tg-felg-MP0880-Ab-2Anti-Feline NKAIN1 monoclonal antibodyFeline
GM-Tg-cang-MP0880-Ab-1/ GM-Tg-cang-MP0880-Ab-2Anti-Canine NKAIN1 monoclonal antibodyCanine
GM-Tg-bovg-MP0880-Ab-1/ GM-Tg-bovg-MP0880-Ab-2Anti-Bovine NKAIN1 monoclonal antibodyBovine
GM-Tg-equg-MP0880-Ab-1/ GM-Tg-equg-MP0880-Ab-2Anti-Equine NKAIN1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0880-Ab-1/ GM-Tg-hg-MP0880-Ab-2; GM-Tg-rg-MP0880-Ab-1/ GM-Tg-rg-MP0880-Ab-2;
GM-Tg-mg-MP0880-Ab-1/ GM-Tg-mg-MP0880-Ab-2; GM-Tg-cynog-MP0880-Ab-1/ GM-Tg-cynog-MP0880-Ab-2;
GM-Tg-felg-MP0880-Ab-1/ GM-Tg-felg-MP0880-Ab-2; GM-Tg-cang-MP0880-Ab-1/ GM-Tg-cang-MP0880-Ab-2;
GM-Tg-bovg-MP0880-Ab-1/ GM-Tg-bovg-MP0880-Ab-2; GM-Tg-equg-MP0880-Ab-1/ GM-Tg-equg-MP0880-Ab-2
Products NameAnti-NKAIN1 monoclonal antibody
Formatmab
Target NameNKAIN1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NKAIN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NKAI1/ NKAIN1/ FAM77C VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0880
    Target NameNKAIN1
    Gene ID79570,67149,500557,704595,611917,101094521,618218,100070490
    Gene Symbol and Synonyms2610200G18Rik,2810426C15Rik,FAM77C,NKAIN1,RGD1561205
    Uniprot AccessionQ4KMZ8
    Uniprot Entry NameNKAI1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000084628
    Target ClassificationN/A

    The target: NKAIN1, gene name: NKAIN1, also named as FAM77C. NKAIN1 is a member of a family of mammalian proteins with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.