Anti-MGST2/ GST2/ MGST-II monoclonal antibody

Anti-MGST2/ GST2/ MGST-II antibody for FACS & in-vivo assay

Target products collectionGo to MGST2/MGST2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0812-Ab-1/ GM-Tg-hg-MP0812-Ab-2Anti-Human MGST2 monoclonal antibodyHuman
GM-Tg-rg-MP0812-Ab-1/ GM-Tg-rg-MP0812-Ab-2Anti-Rat MGST2 monoclonal antibodyRat
GM-Tg-mg-MP0812-Ab-1/ GM-Tg-mg-MP0812-Ab-2Anti-Mouse MGST2 monoclonal antibodyMouse
GM-Tg-cynog-MP0812-Ab-1/ GM-Tg-cynog-MP0812-Ab-2Anti-Cynomolgus/ Rhesus macaque MGST2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0812-Ab-1/ GM-Tg-felg-MP0812-Ab-2Anti-Feline MGST2 monoclonal antibodyFeline
GM-Tg-cang-MP0812-Ab-1/ GM-Tg-cang-MP0812-Ab-2Anti-Canine MGST2 monoclonal antibodyCanine
GM-Tg-bovg-MP0812-Ab-1/ GM-Tg-bovg-MP0812-Ab-2Anti-Bovine MGST2 monoclonal antibodyBovine
GM-Tg-equg-MP0812-Ab-1/ GM-Tg-equg-MP0812-Ab-2Anti-Equine MGST2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0812-Ab-1/ GM-Tg-hg-MP0812-Ab-2; GM-Tg-rg-MP0812-Ab-1/ GM-Tg-rg-MP0812-Ab-2;
GM-Tg-mg-MP0812-Ab-1/ GM-Tg-mg-MP0812-Ab-2; GM-Tg-cynog-MP0812-Ab-1/ GM-Tg-cynog-MP0812-Ab-2;
GM-Tg-felg-MP0812-Ab-1/ GM-Tg-felg-MP0812-Ab-2; GM-Tg-cang-MP0812-Ab-1/ GM-Tg-cang-MP0812-Ab-2;
GM-Tg-bovg-MP0812-Ab-1/ GM-Tg-bovg-MP0812-Ab-2; GM-Tg-equg-MP0812-Ab-1/ GM-Tg-equg-MP0812-Ab-2
Products NameAnti-MGST2 monoclonal antibody
Formatmab
Target NameMGST2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MGST2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MGST2/ GST2/ MGST-II VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0812
    Target NameMGST2
    Gene ID4258,211666,295037,697983,476078,101090936,615552,100630562
    Gene Symbol and SynonymsGST2,MGST-II,MGST2
    Uniprot AccessionQ99735,Q2KJG4
    Uniprot Entry NameMGST2_HUMAN,MGST2_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000085871
    Target ClassificationN/A

    The target: MGST2, gene name: MGST2, also named as GST2, MGST-II. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.