Anti-MDGA2/ MAMDC1/ c14_5286 monoclonal antibody

Anti-MDGA2/ MAMDC1/ c14_5286 antibody for FACS & in-vivo assay

Target products collectionGo to MDGA2/MDGA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0803-Ab-1/ GM-Tg-hg-MP0803-Ab-2Anti-Human MDGA2 monoclonal antibodyHuman
GM-Tg-rg-MP0803-Ab-1/ GM-Tg-rg-MP0803-Ab-2Anti-Rat MDGA2 monoclonal antibodyRat
GM-Tg-mg-MP0803-Ab-1/ GM-Tg-mg-MP0803-Ab-2Anti-Mouse MDGA2 monoclonal antibodyMouse
GM-Tg-cynog-MP0803-Ab-1/ GM-Tg-cynog-MP0803-Ab-2Anti-Cynomolgus/ Rhesus macaque MDGA2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0803-Ab-1/ GM-Tg-felg-MP0803-Ab-2Anti-Feline MDGA2 monoclonal antibodyFeline
GM-Tg-cang-MP0803-Ab-1/ GM-Tg-cang-MP0803-Ab-2Anti-Canine MDGA2 monoclonal antibodyCanine
GM-Tg-bovg-MP0803-Ab-1/ GM-Tg-bovg-MP0803-Ab-2Anti-Bovine MDGA2 monoclonal antibodyBovine
GM-Tg-equg-MP0803-Ab-1/ GM-Tg-equg-MP0803-Ab-2Anti-Equine MDGA2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0803-Ab-1/ GM-Tg-hg-MP0803-Ab-2; GM-Tg-rg-MP0803-Ab-1/ GM-Tg-rg-MP0803-Ab-2;
GM-Tg-mg-MP0803-Ab-1/ GM-Tg-mg-MP0803-Ab-2; GM-Tg-cynog-MP0803-Ab-1/ GM-Tg-cynog-MP0803-Ab-2;
GM-Tg-felg-MP0803-Ab-1/ GM-Tg-felg-MP0803-Ab-2; GM-Tg-cang-MP0803-Ab-1/ GM-Tg-cang-MP0803-Ab-2;
GM-Tg-bovg-MP0803-Ab-1/ GM-Tg-bovg-MP0803-Ab-2; GM-Tg-equg-MP0803-Ab-1/ GM-Tg-equg-MP0803-Ab-2
Products NameAnti-MDGA2 monoclonal antibody
Formatmab
Target NameMDGA2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MDGA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MDGA2/ MAMDC1/ c14_5286 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0803
    Target NameMDGA2
    Gene ID161357,320772,314180,703237,480310,101090022,537506,100064457
    Gene Symbol and Synonyms6720489L24Rik,9330209L04Rik,Adp,c14_5286,MAMDC1,MDGA2,Tg(Prnp-PFN1*G118V)838Kiaei
    Uniprot AccessionQ7Z553,P60756
    Uniprot Entry NameMDGA2_HUMAN,MDGA2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139915
    Target ClassificationN/A

    The target: MDGA2, gene name: MDGA2, also named as MAMDC1, c14_5286. Predicted to be involved in regulation of presynapse assembly; regulation of synaptic membrane adhesion; and spinal cord motor neuron differentiation. Predicted to act upstream of or within neuron migration and pattern specification process. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in GABA-ergic synapse and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.