Anti-PLPR5/ PLPPR5/ LPPR5 monoclonal antibody

Anti-PLPR5/ PLPPR5/ LPPR5 antibody for FACS & in-vivo assay

Target products collectionGo to PLPPR5/PLPPR5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0743-Ab-1/ GM-Tg-hg-MP0743-Ab-2Anti-Human PLPPR5 monoclonal antibodyHuman
GM-Tg-rg-MP0743-Ab-1/ GM-Tg-rg-MP0743-Ab-2Anti-Rat PLPPR5 monoclonal antibodyRat
GM-Tg-mg-MP0743-Ab-1/ GM-Tg-mg-MP0743-Ab-2Anti-Mouse PLPPR5 monoclonal antibodyMouse
GM-Tg-cynog-MP0743-Ab-1/ GM-Tg-cynog-MP0743-Ab-2Anti-Cynomolgus/ Rhesus macaque PLPPR5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0743-Ab-1/ GM-Tg-felg-MP0743-Ab-2Anti-Feline PLPPR5 monoclonal antibodyFeline
GM-Tg-cang-MP0743-Ab-1/ GM-Tg-cang-MP0743-Ab-2Anti-Canine PLPPR5 monoclonal antibodyCanine
GM-Tg-bovg-MP0743-Ab-1/ GM-Tg-bovg-MP0743-Ab-2Anti-Bovine PLPPR5 monoclonal antibodyBovine
GM-Tg-equg-MP0743-Ab-1/ GM-Tg-equg-MP0743-Ab-2Anti-Equine PLPPR5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0743-Ab-1/ GM-Tg-hg-MP0743-Ab-2; GM-Tg-rg-MP0743-Ab-1/ GM-Tg-rg-MP0743-Ab-2;
GM-Tg-mg-MP0743-Ab-1/ GM-Tg-mg-MP0743-Ab-2; GM-Tg-cynog-MP0743-Ab-1/ GM-Tg-cynog-MP0743-Ab-2;
GM-Tg-felg-MP0743-Ab-1/ GM-Tg-felg-MP0743-Ab-2; GM-Tg-cang-MP0743-Ab-1/ GM-Tg-cang-MP0743-Ab-2;
GM-Tg-bovg-MP0743-Ab-1/ GM-Tg-bovg-MP0743-Ab-2; GM-Tg-equg-MP0743-Ab-1/ GM-Tg-equg-MP0743-Ab-2
Products NameAnti-PLPPR5 monoclonal antibody
Formatmab
Target NamePLPPR5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLPPR5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLPR5/ PLPPR5/ LPPR5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0743
    Target NamePLPPR5
    Gene ID163404,75769,310812,710549,479934,101089633,100848786,100056696
    Gene Symbol and Synonyms4833424O15Rik,LPPR5,PAP2,PAP2D,PLPPR5,PRG-5,PRG5,RGD1309567
    Uniprot AccessionQ32ZL2
    Uniprot Entry NamePLPR5_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000117598
    Target ClassificationN/A

    The target: PLPPR5, gene name: PLPPR5, also named as LPPR5, PAP2, PAP2D, PRG5. The protein encoded by this gene is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.