Anti-I20RB/ IL20RB/ DIRS1 monoclonal antibody

Anti-I20RB/ IL20RB/ DIRS1 antibody for FACS & in-vivo assay

Target products collectionGo to IL20RB/IL20RB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0624-Ab-1/ GM-Tg-hg-MP0624-Ab-2Anti-Human IL20RB monoclonal antibodyHuman
GM-Tg-rg-MP0624-Ab-1/ GM-Tg-rg-MP0624-Ab-2Anti-Rat IL20RB monoclonal antibodyRat
GM-Tg-mg-MP0624-Ab-1/ GM-Tg-mg-MP0624-Ab-2Anti-Mouse IL20RB monoclonal antibodyMouse
GM-Tg-cynog-MP0624-Ab-1/ GM-Tg-cynog-MP0624-Ab-2Anti-Cynomolgus/ Rhesus macaque IL20RB monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0624-Ab-1/ GM-Tg-felg-MP0624-Ab-2Anti-Feline IL20RB monoclonal antibodyFeline
GM-Tg-cang-MP0624-Ab-1/ GM-Tg-cang-MP0624-Ab-2Anti-Canine IL20RB monoclonal antibodyCanine
GM-Tg-bovg-MP0624-Ab-1/ GM-Tg-bovg-MP0624-Ab-2Anti-Bovine IL20RB monoclonal antibodyBovine
GM-Tg-equg-MP0624-Ab-1/ GM-Tg-equg-MP0624-Ab-2Anti-Equine IL20RB monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0624-Ab-1/ GM-Tg-hg-MP0624-Ab-2; GM-Tg-rg-MP0624-Ab-1/ GM-Tg-rg-MP0624-Ab-2;
GM-Tg-mg-MP0624-Ab-1/ GM-Tg-mg-MP0624-Ab-2; GM-Tg-cynog-MP0624-Ab-1/ GM-Tg-cynog-MP0624-Ab-2;
GM-Tg-felg-MP0624-Ab-1/ GM-Tg-felg-MP0624-Ab-2; GM-Tg-cang-MP0624-Ab-1/ GM-Tg-cang-MP0624-Ab-2;
GM-Tg-bovg-MP0624-Ab-1/ GM-Tg-bovg-MP0624-Ab-2; GM-Tg-equg-MP0624-Ab-1/ GM-Tg-equg-MP0624-Ab-2
Products NameAnti-IL20RB monoclonal antibody
Formatmab
Target NameIL20RB
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL20RB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species I20RB/ IL20RB/ DIRS1 VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-MP0624-Ag-1Interleukin 20 receptor subunit beta (IL20RB) protein


    Target information

    Target IDGM-MP0624
    Target NameIL20RB
    Gene ID53833,213208,501043,716769,610961,101081159,534581,100066346
    Gene Symbol and SynonymsDIRS1,FNDC6,Gm186,IL-20R2,Il20R2,IL20RB,RGD1566151
    Uniprot AccessionQ6UXL0
    Uniprot Entry NameI20RB_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000174564
    Target ClassificationN/A

    The target: IL20RB, gene name: IL20RB, also named as DIRS1, FNDC6, IL-20R2. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.