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Anti-I20RA/ IL20RA/ CRF2-8 monoclonal antibody
Anti-I20RA/ IL20RA/ CRF2-8 antibody for FACS & in-vivo assay
Go to IL20RA/IL20RA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0623-Ab-1/ GM-Tg-hg-MP0623-Ab-2 | Anti-Human IL20RA monoclonal antibody | Human |
| GM-Tg-rg-MP0623-Ab-1/ GM-Tg-rg-MP0623-Ab-2 | Anti-Rat IL20RA monoclonal antibody | Rat |
| GM-Tg-mg-MP0623-Ab-1/ GM-Tg-mg-MP0623-Ab-2 | Anti-Mouse IL20RA monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0623-Ab-1/ GM-Tg-cynog-MP0623-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL20RA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0623-Ab-1/ GM-Tg-felg-MP0623-Ab-2 | Anti-Feline IL20RA monoclonal antibody | Feline |
| GM-Tg-cang-MP0623-Ab-1/ GM-Tg-cang-MP0623-Ab-2 | Anti-Canine IL20RA monoclonal antibody | Canine |
| GM-Tg-bovg-MP0623-Ab-1/ GM-Tg-bovg-MP0623-Ab-2 | Anti-Bovine IL20RA monoclonal antibody | Bovine |
| GM-Tg-equg-MP0623-Ab-1/ GM-Tg-equg-MP0623-Ab-2 | Anti-Equine IL20RA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0623-Ab-1/ GM-Tg-hg-MP0623-Ab-2; GM-Tg-rg-MP0623-Ab-1/ GM-Tg-rg-MP0623-Ab-2; GM-Tg-mg-MP0623-Ab-1/ GM-Tg-mg-MP0623-Ab-2; GM-Tg-cynog-MP0623-Ab-1/ GM-Tg-cynog-MP0623-Ab-2; GM-Tg-felg-MP0623-Ab-1/ GM-Tg-felg-MP0623-Ab-2; GM-Tg-cang-MP0623-Ab-1/ GM-Tg-cang-MP0623-Ab-2; GM-Tg-bovg-MP0623-Ab-1/ GM-Tg-bovg-MP0623-Ab-2; GM-Tg-equg-MP0623-Ab-1/ GM-Tg-equg-MP0623-Ab-2 |
| Products Name | Anti-IL20RA monoclonal antibody |
| Format | mab |
| Target Name | IL20RA |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL20RA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species I20RA/ IL20RA/ CRF2-8 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP0623-Ag-1 | Interleukin 20 receptor subunit alpha (IL20RA) protein |
Target information
| Target ID | GM-MP0623 |
| Target Name | IL20RA |
| Gene ID | 53832,237313,308716,704890,484002,101086565,509038,100073190 |
| Gene Symbol and Synonyms | CRF2-8,E230031K19,IL-20R-alpha,IL-20R1,IL-20RA,IL20RA |
| Uniprot Accession | Q9UHF4 |
| Uniprot Entry Name | I20RA_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000016402 |
| Target Classification | N/A |
The target: IL20RA, gene name: IL20RA, also named as CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA. This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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