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Anti-GUC2F/ GUCY2F/ CYGF monoclonal antibody
Anti-GUC2F/ GUCY2F/ CYGF antibody for FACS & in-vivo assay
Go to GUCY2F/GUCY2F products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0564-Ab-1/ GM-Tg-hg-MP0564-Ab-2 | Anti-Human GUCY2F monoclonal antibody | Human |
| GM-Tg-rg-MP0564-Ab-1/ GM-Tg-rg-MP0564-Ab-2 | Anti-Rat GUCY2F monoclonal antibody | Rat |
| GM-Tg-mg-MP0564-Ab-1/ GM-Tg-mg-MP0564-Ab-2 | Anti-Mouse GUCY2F monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0564-Ab-1/ GM-Tg-cynog-MP0564-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GUCY2F monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0564-Ab-1/ GM-Tg-felg-MP0564-Ab-2 | Anti-Feline GUCY2F monoclonal antibody | Feline |
| GM-Tg-cang-MP0564-Ab-1/ GM-Tg-cang-MP0564-Ab-2 | Anti-Canine GUCY2F monoclonal antibody | Canine |
| GM-Tg-bovg-MP0564-Ab-1/ GM-Tg-bovg-MP0564-Ab-2 | Anti-Bovine GUCY2F monoclonal antibody | Bovine |
| GM-Tg-equg-MP0564-Ab-1/ GM-Tg-equg-MP0564-Ab-2 | Anti-Equine GUCY2F monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0564-Ab-1/ GM-Tg-hg-MP0564-Ab-2; GM-Tg-rg-MP0564-Ab-1/ GM-Tg-rg-MP0564-Ab-2; GM-Tg-mg-MP0564-Ab-1/ GM-Tg-mg-MP0564-Ab-2; GM-Tg-cynog-MP0564-Ab-1/ GM-Tg-cynog-MP0564-Ab-2; GM-Tg-felg-MP0564-Ab-1/ GM-Tg-felg-MP0564-Ab-2; GM-Tg-cang-MP0564-Ab-1/ GM-Tg-cang-MP0564-Ab-2; GM-Tg-bovg-MP0564-Ab-1/ GM-Tg-bovg-MP0564-Ab-2; GM-Tg-equg-MP0564-Ab-1/ GM-Tg-equg-MP0564-Ab-2 |
| Products Name | Anti-GUCY2F monoclonal antibody |
| Format | mab |
| Target Name | GUCY2F |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GUCY2F benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GUC2F/ GUCY2F/ CYGF VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0564 |
| Target Name | GUCY2F |
| Gene ID | 2986,245650,116556,704485,481016,101090242,282246,100054502 |
| Gene Symbol and Synonyms | A930002I06,CYGF,GC-F,GC2,GUC2DL,GUC2F,GUCY2F,RETGC-2,ROS-GC2 |
| Uniprot Accession | P51841,P51842,O02740 |
| Uniprot Entry Name | GUC2F_HUMAN,GUC2F_RAT,GUC2F_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000101890 |
| Target Classification | N/A |
The target: GUCY2F, gene name: GUCY2F, also named as CYGF, GC-F, GUC2DL, GUC2F, RETGC-2, ROS-GC2. The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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