Anti-PSYR/ GPR65/ TDAG8 monoclonal antibody

Anti-PSYR/ GPR65/ TDAG8 antibody for FACS & in-vivo assay

Target products collectionGo to GPR65/GPR65 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0543-Ab-1/ GM-Tg-hg-MP0543-Ab-2Anti-Human GPR65 monoclonal antibodyHuman
GM-Tg-rg-MP0543-Ab-1/ GM-Tg-rg-MP0543-Ab-2Anti-Rat GPR65 monoclonal antibodyRat
GM-Tg-mg-MP0543-Ab-1/ GM-Tg-mg-MP0543-Ab-2Anti-Mouse GPR65 monoclonal antibodyMouse
GM-Tg-cynog-MP0543-Ab-1/ GM-Tg-cynog-MP0543-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR65 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0543-Ab-1/ GM-Tg-felg-MP0543-Ab-2Anti-Feline GPR65 monoclonal antibodyFeline
GM-Tg-cang-MP0543-Ab-1/ GM-Tg-cang-MP0543-Ab-2Anti-Canine GPR65 monoclonal antibodyCanine
GM-Tg-bovg-MP0543-Ab-1/ GM-Tg-bovg-MP0543-Ab-2Anti-Bovine GPR65 monoclonal antibodyBovine
GM-Tg-equg-MP0543-Ab-1/ GM-Tg-equg-MP0543-Ab-2Anti-Equine GPR65 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0543-Ab-1/ GM-Tg-hg-MP0543-Ab-2; GM-Tg-rg-MP0543-Ab-1/ GM-Tg-rg-MP0543-Ab-2;
GM-Tg-mg-MP0543-Ab-1/ GM-Tg-mg-MP0543-Ab-2; GM-Tg-cynog-MP0543-Ab-1/ GM-Tg-cynog-MP0543-Ab-2;
GM-Tg-felg-MP0543-Ab-1/ GM-Tg-felg-MP0543-Ab-2; GM-Tg-cang-MP0543-Ab-1/ GM-Tg-cang-MP0543-Ab-2;
GM-Tg-bovg-MP0543-Ab-1/ GM-Tg-bovg-MP0543-Ab-2; GM-Tg-equg-MP0543-Ab-1/ GM-Tg-equg-MP0543-Ab-2
Products NameAnti-GPR65 monoclonal antibody
Formatmab
Target NameGPR65
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR65 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PSYR/ GPR65/ TDAG8 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLV000613human GPR65 Lentivirus particle
    ORF Viral VectorpGMLV000613human GPR65 Lentivirus plasmid


    Target information

    Target IDGM-MP0543
    Target NameGPR65
    Gene ID8477,14744,299242,693449,490821,101091206,788507,100061785
    Gene Symbol and SynonymsDig1,Gpcr25,GPR65,hTDAG8,TDAG8
    Uniprot AccessionQ8IYL9
    Uniprot Entry NamePSYR_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000140030
    Target ClassificationGPCR

    The target: GPR65, gene name: GPR65, also named as TDAG8, hTDAG8. Enables G protein-coupled receptor activity. Involved in several processes, including actin cytoskeleton reorganization; activation of GTPase activity; and positive regulation of stress fiber assembly. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.