Anti-GPR61/ BALGR/ GPCR3 monoclonal antibody

Anti-GPR61/ BALGR/ GPCR3 antibody for FACS & in-vivo assay

Target products collectionGo to GPR61/GPR61 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0540-Ab-1/ GM-Tg-hg-MP0540-Ab-2Anti-Human GPR61 monoclonal antibodyHuman
GM-Tg-rg-MP0540-Ab-1/ GM-Tg-rg-MP0540-Ab-2Anti-Rat GPR61 monoclonal antibodyRat
GM-Tg-mg-MP0540-Ab-1/ GM-Tg-mg-MP0540-Ab-2Anti-Mouse GPR61 monoclonal antibodyMouse
GM-Tg-cynog-MP0540-Ab-1/ GM-Tg-cynog-MP0540-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR61 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0540-Ab-1/ GM-Tg-felg-MP0540-Ab-2Anti-Feline GPR61 monoclonal antibodyFeline
GM-Tg-cang-MP0540-Ab-1/ GM-Tg-cang-MP0540-Ab-2Anti-Canine GPR61 monoclonal antibodyCanine
GM-Tg-bovg-MP0540-Ab-1/ GM-Tg-bovg-MP0540-Ab-2Anti-Bovine GPR61 monoclonal antibodyBovine
GM-Tg-equg-MP0540-Ab-1/ GM-Tg-equg-MP0540-Ab-2Anti-Equine GPR61 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0540-Ab-1/ GM-Tg-hg-MP0540-Ab-2; GM-Tg-rg-MP0540-Ab-1/ GM-Tg-rg-MP0540-Ab-2;
GM-Tg-mg-MP0540-Ab-1/ GM-Tg-mg-MP0540-Ab-2; GM-Tg-cynog-MP0540-Ab-1/ GM-Tg-cynog-MP0540-Ab-2;
GM-Tg-felg-MP0540-Ab-1/ GM-Tg-felg-MP0540-Ab-2; GM-Tg-cang-MP0540-Ab-1/ GM-Tg-cang-MP0540-Ab-2;
GM-Tg-bovg-MP0540-Ab-1/ GM-Tg-bovg-MP0540-Ab-2; GM-Tg-equg-MP0540-Ab-1/ GM-Tg-equg-MP0540-Ab-2
Products NameAnti-GPR61 monoclonal antibody
Formatmab
Target NameGPR61
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR61 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR61/ BALGR/ GPCR3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0540
    Target NameGPR61
    Gene ID83873,229714,310780,699055,479914,101100070,540581,100061655
    Gene Symbol and SynonymsBALGR,GPCR3,GPR61
    Uniprot AccessionQ9BZJ8
    Uniprot Entry NameGPR61_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156097
    Target ClassificationGPCR

    The target: GPR61, gene name: GPR61, also named as BALGR, GPCR3. This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.