Anti-G37L1/ GPR37L1/ ET(B)R-LP-2 monoclonal antibody

Anti-G37L1/ GPR37L1/ ET(B)R-LP-2 antibody for FACS & in-vivo assay

Target products collectionGo to GPR37L1/GPR37L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0534-Ab-1/ GM-Tg-hg-MP0534-Ab-2Anti-Human GPR37L1 monoclonal antibodyHuman
GM-Tg-rg-MP0534-Ab-1/ GM-Tg-rg-MP0534-Ab-2Anti-Rat GPR37L1 monoclonal antibodyRat
GM-Tg-mg-MP0534-Ab-1/ GM-Tg-mg-MP0534-Ab-2Anti-Mouse GPR37L1 monoclonal antibodyMouse
GM-Tg-cynog-MP0534-Ab-1/ GM-Tg-cynog-MP0534-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR37L1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0534-Ab-1/ GM-Tg-felg-MP0534-Ab-2Anti-Feline GPR37L1 monoclonal antibodyFeline
GM-Tg-cang-MP0534-Ab-1/ GM-Tg-cang-MP0534-Ab-2Anti-Canine GPR37L1 monoclonal antibodyCanine
GM-Tg-bovg-MP0534-Ab-1/ GM-Tg-bovg-MP0534-Ab-2Anti-Bovine GPR37L1 monoclonal antibodyBovine
GM-Tg-equg-MP0534-Ab-1/ GM-Tg-equg-MP0534-Ab-2Anti-Equine GPR37L1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0534-Ab-1/ GM-Tg-hg-MP0534-Ab-2; GM-Tg-rg-MP0534-Ab-1/ GM-Tg-rg-MP0534-Ab-2;
GM-Tg-mg-MP0534-Ab-1/ GM-Tg-mg-MP0534-Ab-2; GM-Tg-cynog-MP0534-Ab-1/ GM-Tg-cynog-MP0534-Ab-2;
GM-Tg-felg-MP0534-Ab-1/ GM-Tg-felg-MP0534-Ab-2; GM-Tg-cang-MP0534-Ab-1/ GM-Tg-cang-MP0534-Ab-2;
GM-Tg-bovg-MP0534-Ab-1/ GM-Tg-bovg-MP0534-Ab-2; GM-Tg-equg-MP0534-Ab-1/ GM-Tg-equg-MP0534-Ab-2
Products NameAnti-GPR37L1 monoclonal antibody
Formatmab
Target NameGPR37L1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR37L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species G37L1/ GPR37L1/ ET(B)R-LP-2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0534
    Target NameGPR37L1
    Gene ID9283,171469,252939,706485,607285,101097865,527572,100052137
    Gene Symbol and SynonymsCAG-18,D0Kist8,ET(B)R-LP-2,ETBR-LP-2,ETBRLP2,GPR37L1
    Uniprot AccessionO60883,Q9QYC5,Q17QD8
    Uniprot Entry NameG37L1_HUMAN,G37L1_RAT,G37L1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170075
    Target ClassificationGPCR

    The target: GPR37L1, gene name: GPR37L1, also named as ET(B)R-LP-2, ETBR-LP-2, ETBRLP2. Enables G protein-coupled peptide receptor activity; peptide binding activity; and prosaposin receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and positive regulation of MAPK cascade. Located in plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.