Anti-GPR27/ SREB1 monoclonal antibody

Anti-GPR27/ SREB1 antibody for FACS & in-vivo assay

Target products collectionGo to GPR27/GPR27 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0531-Ab-1/ GM-Tg-hg-MP0531-Ab-2Anti-Human GPR27 monoclonal antibodyHuman
GM-Tg-rg-MP0531-Ab-1/ GM-Tg-rg-MP0531-Ab-2Anti-Rat GPR27 monoclonal antibodyRat
GM-Tg-mg-MP0531-Ab-1/ GM-Tg-mg-MP0531-Ab-2Anti-Mouse GPR27 monoclonal antibodyMouse
GM-Tg-cynog-MP0531-Ab-1/ GM-Tg-cynog-MP0531-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR27 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0531-Ab-1/ GM-Tg-felg-MP0531-Ab-2Anti-Feline GPR27 monoclonal antibodyFeline
GM-Tg-cang-MP0531-Ab-1/ GM-Tg-cang-MP0531-Ab-2Anti-Canine GPR27 monoclonal antibodyCanine
GM-Tg-bovg-MP0531-Ab-1/ GM-Tg-bovg-MP0531-Ab-2Anti-Bovine GPR27 monoclonal antibodyBovine
GM-Tg-equg-MP0531-Ab-1/ GM-Tg-equg-MP0531-Ab-2Anti-Equine GPR27 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0531-Ab-1/ GM-Tg-hg-MP0531-Ab-2; GM-Tg-rg-MP0531-Ab-1/ GM-Tg-rg-MP0531-Ab-2;
GM-Tg-mg-MP0531-Ab-1/ GM-Tg-mg-MP0531-Ab-2; GM-Tg-cynog-MP0531-Ab-1/ GM-Tg-cynog-MP0531-Ab-2;
GM-Tg-felg-MP0531-Ab-1/ GM-Tg-felg-MP0531-Ab-2; GM-Tg-cang-MP0531-Ab-1/ GM-Tg-cang-MP0531-Ab-2;
GM-Tg-bovg-MP0531-Ab-1/ GM-Tg-bovg-MP0531-Ab-2; GM-Tg-equg-MP0531-Ab-1/ GM-Tg-equg-MP0531-Ab-2
Products NameAnti-GPR27 monoclonal antibody
Formatmab
Target NameGPR27
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR27 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR27/ SREB1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0531
    Target NameGPR27
    Gene ID2850,14761,65275,720525,119864656,111559442,782069,111768463
    Gene Symbol and SynonymsGPR27,SREB1
    Uniprot AccessionQ9NS67,Q9JJH3
    Uniprot Entry NameGPR27_HUMAN,GPR27_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170837
    Target ClassificationGPCR

    The target: GPR27, gene name: GPR27, also named as SREB1. GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.