Anti-AGRA3/ ADGRA3/ GPR125 monoclonal antibody

Anti-AGRA3/ ADGRA3/ GPR125 antibody for FACS & in-vivo assay

Target products collectionGo to ADGRA3/ADGRA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0504-Ab-1/ GM-Tg-hg-MP0504-Ab-2Anti-Human ADGRA3 monoclonal antibodyHuman
GM-Tg-rg-MP0504-Ab-1/ GM-Tg-rg-MP0504-Ab-2Anti-Rat ADGRA3 monoclonal antibodyRat
GM-Tg-mg-MP0504-Ab-1/ GM-Tg-mg-MP0504-Ab-2Anti-Mouse ADGRA3 monoclonal antibodyMouse
GM-Tg-cynog-MP0504-Ab-1/ GM-Tg-cynog-MP0504-Ab-2Anti-Cynomolgus/ Rhesus macaque ADGRA3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0504-Ab-1/ GM-Tg-felg-MP0504-Ab-2Anti-Feline ADGRA3 monoclonal antibodyFeline
GM-Tg-cang-MP0504-Ab-1/ GM-Tg-cang-MP0504-Ab-2Anti-Canine ADGRA3 monoclonal antibodyCanine
GM-Tg-bovg-MP0504-Ab-1/ GM-Tg-bovg-MP0504-Ab-2Anti-Bovine ADGRA3 monoclonal antibodyBovine
GM-Tg-equg-MP0504-Ab-1/ GM-Tg-equg-MP0504-Ab-2Anti-Equine ADGRA3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0504-Ab-1/ GM-Tg-hg-MP0504-Ab-2; GM-Tg-rg-MP0504-Ab-1/ GM-Tg-rg-MP0504-Ab-2;
GM-Tg-mg-MP0504-Ab-1/ GM-Tg-mg-MP0504-Ab-2; GM-Tg-cynog-MP0504-Ab-1/ GM-Tg-cynog-MP0504-Ab-2;
GM-Tg-felg-MP0504-Ab-1/ GM-Tg-felg-MP0504-Ab-2; GM-Tg-cang-MP0504-Ab-1/ GM-Tg-cang-MP0504-Ab-2;
GM-Tg-bovg-MP0504-Ab-1/ GM-Tg-bovg-MP0504-Ab-2; GM-Tg-equg-MP0504-Ab-1/ GM-Tg-equg-MP0504-Ab-2
Products NameAnti-ADGRA3 monoclonal antibody
Formatmab
Target NameADGRA3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADGRA3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species AGRA3/ ADGRA3/ GPR125 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0504
    Target NameADGRA3
    Gene ID166647,70693,305408,715618,488859,101082650,541147,100068039
    Gene Symbol and Synonyms3830613O22Rik,ADGRA3,GPR125,PGR21,Tem5-like,TEM5L
    Uniprot AccessionQ8IWK6
    Uniprot Entry NameAGRA3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000152990
    Target ClassificationGPCR

    The target: ADGRA3, gene name: ADGRA3, also named as GPR125, PGR21, TEM5L. This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.