Anti-GPIX/ GP9/ CD42a monoclonal antibody

Anti-GPIX/ GP9/ CD42a antibody for FACS & in-vivo assay

Target products collectionGo to GP9/GP9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0489-Ab-1/ GM-Tg-hg-MP0489-Ab-2Anti-Human GP9 monoclonal antibodyHuman
GM-Tg-rg-MP0489-Ab-1/ GM-Tg-rg-MP0489-Ab-2Anti-Rat GP9 monoclonal antibodyRat
GM-Tg-mg-MP0489-Ab-1/ GM-Tg-mg-MP0489-Ab-2Anti-Mouse GP9 monoclonal antibodyMouse
GM-Tg-cynog-MP0489-Ab-1/ GM-Tg-cynog-MP0489-Ab-2Anti-Cynomolgus/ Rhesus macaque GP9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0489-Ab-1/ GM-Tg-felg-MP0489-Ab-2Anti-Feline GP9 monoclonal antibodyFeline
GM-Tg-cang-MP0489-Ab-1/ GM-Tg-cang-MP0489-Ab-2Anti-Canine GP9 monoclonal antibodyCanine
GM-Tg-bovg-MP0489-Ab-1/ GM-Tg-bovg-MP0489-Ab-2Anti-Bovine GP9 monoclonal antibodyBovine
GM-Tg-equg-MP0489-Ab-1/ GM-Tg-equg-MP0489-Ab-2Anti-Equine GP9 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0489-Ab-1/ GM-Tg-hg-MP0489-Ab-2; GM-Tg-rg-MP0489-Ab-1/ GM-Tg-rg-MP0489-Ab-2;
GM-Tg-mg-MP0489-Ab-1/ GM-Tg-mg-MP0489-Ab-2; GM-Tg-cynog-MP0489-Ab-1/ GM-Tg-cynog-MP0489-Ab-2;
GM-Tg-felg-MP0489-Ab-1/ GM-Tg-felg-MP0489-Ab-2; GM-Tg-cang-MP0489-Ab-1/ GM-Tg-cang-MP0489-Ab-2;
GM-Tg-bovg-MP0489-Ab-1/ GM-Tg-bovg-MP0489-Ab-2; GM-Tg-equg-MP0489-Ab-1/ GM-Tg-equg-MP0489-Ab-2
Products NameAnti-GP9 monoclonal antibody
Formatmab
Target NameGP9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GP9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPIX/ GP9/ CD42a VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0489
    Target NameGP9
    Gene ID2815,54368,502858,704202,609630,101084179,617668,102149779
    Gene Symbol and SynonymsCd42,CD42a,GP9,GPIX
    Uniprot AccessionP14770
    Uniprot Entry NameGPIX_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169704
    Target ClassificationN/A

    The target: GP9, gene name: GP9, also named as CD42a, GPIX. This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.