Anti-EQTN/ AFAF/ C9orf11 monoclonal antibody

Anti-EQTN/ AFAF/ C9orf11 antibody for FACS & in-vivo assay

Target products collectionGo to EQTN/EQTN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0420-Ab-1/ GM-Tg-hg-MP0420-Ab-2Anti-Human EQTN monoclonal antibodyHuman
GM-Tg-rg-MP0420-Ab-1/ GM-Tg-rg-MP0420-Ab-2Anti-Rat EQTN monoclonal antibodyRat
GM-Tg-mg-MP0420-Ab-1/ GM-Tg-mg-MP0420-Ab-2Anti-Mouse EQTN monoclonal antibodyMouse
GM-Tg-cynog-MP0420-Ab-1/ GM-Tg-cynog-MP0420-Ab-2Anti-Cynomolgus/ Rhesus macaque EQTN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0420-Ab-1/ GM-Tg-felg-MP0420-Ab-2Anti-Feline EQTN monoclonal antibodyFeline
GM-Tg-cang-MP0420-Ab-1/ GM-Tg-cang-MP0420-Ab-2Anti-Canine EQTN monoclonal antibodyCanine
GM-Tg-bovg-MP0420-Ab-1/ GM-Tg-bovg-MP0420-Ab-2Anti-Bovine EQTN monoclonal antibodyBovine
GM-Tg-equg-MP0420-Ab-1/ GM-Tg-equg-MP0420-Ab-2Anti-Equine EQTN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0420-Ab-1/ GM-Tg-hg-MP0420-Ab-2; GM-Tg-rg-MP0420-Ab-1/ GM-Tg-rg-MP0420-Ab-2;
GM-Tg-mg-MP0420-Ab-1/ GM-Tg-mg-MP0420-Ab-2; GM-Tg-cynog-MP0420-Ab-1/ GM-Tg-cynog-MP0420-Ab-2;
GM-Tg-felg-MP0420-Ab-1/ GM-Tg-felg-MP0420-Ab-2; GM-Tg-cang-MP0420-Ab-1/ GM-Tg-cang-MP0420-Ab-2;
GM-Tg-bovg-MP0420-Ab-1/ GM-Tg-bovg-MP0420-Ab-2; GM-Tg-equg-MP0420-Ab-1/ GM-Tg-equg-MP0420-Ab-2
Products NameAnti-EQTN monoclonal antibody
Formatmab
Target NameEQTN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EQTN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EQTN/ AFAF/ C9orf11 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004239mouse Eqtn Lentivirus plasmid
    ORF Viral VectorvGMLPm004239mouse Eqtn Lentivirus particle


    Target information

    Target IDGM-MP0420
    Target NameEQTN
    Gene ID54586,67753,500502,707334,611648,101094055,615968,100067008
    Gene Symbol and Synonyms1700028B15Rik,4930579C15Rik,AFAF,C11H9orf11,C15H9orf11,C8H9orf11,C9orf11,Eqtl,EQTN,Eqts,SPACA8
    Uniprot AccessionQ9NQ60,Q2LCV6
    Uniprot Entry NameEQTN_HUMAN,EQTN_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000120160
    Target ClassificationN/A

    The target: EQTN, gene name: EQTN, also named as AFAF, C9orf11, SPACA8. Predicted to be involved in acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in acrosomal membrane; early endosome; and nucleus. Predicted to be active in inner acrosomal membrane; outer acrosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.