Anti-DIP2A/ C21orf106/ DIP2 monoclonal antibody

Anti-DIP2A/ C21orf106/ DIP2 antibody for FACS & in-vivo assay

Target products collectionGo to DIP2A/DIP2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0361-Ab-1/ GM-Tg-hg-MP0361-Ab-2Anti-Human DIP2A monoclonal antibodyHuman
GM-Tg-rg-MP0361-Ab-1/ GM-Tg-rg-MP0361-Ab-2Anti-Rat DIP2A monoclonal antibodyRat
GM-Tg-mg-MP0361-Ab-1/ GM-Tg-mg-MP0361-Ab-2Anti-Mouse DIP2A monoclonal antibodyMouse
GM-Tg-cynog-MP0361-Ab-1/ GM-Tg-cynog-MP0361-Ab-2Anti-Cynomolgus/ Rhesus macaque DIP2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0361-Ab-1/ GM-Tg-felg-MP0361-Ab-2Anti-Feline DIP2A monoclonal antibodyFeline
GM-Tg-cang-MP0361-Ab-1/ GM-Tg-cang-MP0361-Ab-2Anti-Canine DIP2A monoclonal antibodyCanine
GM-Tg-bovg-MP0361-Ab-1/ GM-Tg-bovg-MP0361-Ab-2Anti-Bovine DIP2A monoclonal antibodyBovine
GM-Tg-equg-MP0361-Ab-1/ GM-Tg-equg-MP0361-Ab-2Anti-Equine DIP2A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0361-Ab-1/ GM-Tg-hg-MP0361-Ab-2; GM-Tg-rg-MP0361-Ab-1/ GM-Tg-rg-MP0361-Ab-2;
GM-Tg-mg-MP0361-Ab-1/ GM-Tg-mg-MP0361-Ab-2; GM-Tg-cynog-MP0361-Ab-1/ GM-Tg-cynog-MP0361-Ab-2;
GM-Tg-felg-MP0361-Ab-1/ GM-Tg-felg-MP0361-Ab-2; GM-Tg-cang-MP0361-Ab-1/ GM-Tg-cang-MP0361-Ab-2;
GM-Tg-bovg-MP0361-Ab-1/ GM-Tg-bovg-MP0361-Ab-2; GM-Tg-equg-MP0361-Ab-1/ GM-Tg-equg-MP0361-Ab-2
Products NameAnti-DIP2A monoclonal antibody
Formatmab
Target NameDIP2A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DIP2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DIP2A/ C21orf106/ DIP2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0361
    Target NameDIP2A
    Gene ID23181,64451,690211,721788,491614,101101579,518043,100054979
    Gene Symbol and Synonyms4931420H10Rik,C21orf106,DIP2,Dip2-like,DIP2A,Kiaa0184-hp,mKIAA0184
    Uniprot AccessionQ14689
    Uniprot Entry NameDIP2A_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000160305
    Target ClassificationN/A

    The target: DIP2A, gene name: DIP2A, also named as C21orf106, DIP2. The protein encoded by this gene may be involved in axon patterning in the central nervous system. This gene is not highly expressed. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.