Anti-CNTN5/ HNB-2s/ NB-2 monoclonal antibody

Anti-CNTN5/ HNB-2s/ NB-2 antibody for FACS & in-vivo assay

Target products collectionGo to CNTN5/CNTN5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0317-Ab-1/ GM-Tg-hg-MP0317-Ab-2Anti-Human CNTN5 monoclonal antibodyHuman
GM-Tg-rg-MP0317-Ab-1/ GM-Tg-rg-MP0317-Ab-2Anti-Rat CNTN5 monoclonal antibodyRat
GM-Tg-mg-MP0317-Ab-1/ GM-Tg-mg-MP0317-Ab-2Anti-Mouse CNTN5 monoclonal antibodyMouse
GM-Tg-cynog-MP0317-Ab-1/ GM-Tg-cynog-MP0317-Ab-2Anti-Cynomolgus/ Rhesus macaque CNTN5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0317-Ab-1/ GM-Tg-felg-MP0317-Ab-2Anti-Feline CNTN5 monoclonal antibodyFeline
GM-Tg-cang-MP0317-Ab-1/ GM-Tg-cang-MP0317-Ab-2Anti-Canine CNTN5 monoclonal antibodyCanine
GM-Tg-bovg-MP0317-Ab-1/ GM-Tg-bovg-MP0317-Ab-2Anti-Bovine CNTN5 monoclonal antibodyBovine
GM-Tg-equg-MP0317-Ab-1/ GM-Tg-equg-MP0317-Ab-2Anti-Equine CNTN5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0317-Ab-1/ GM-Tg-hg-MP0317-Ab-2; GM-Tg-rg-MP0317-Ab-1/ GM-Tg-rg-MP0317-Ab-2;
GM-Tg-mg-MP0317-Ab-1/ GM-Tg-mg-MP0317-Ab-2; GM-Tg-cynog-MP0317-Ab-1/ GM-Tg-cynog-MP0317-Ab-2;
GM-Tg-felg-MP0317-Ab-1/ GM-Tg-felg-MP0317-Ab-2; GM-Tg-cang-MP0317-Ab-1/ GM-Tg-cang-MP0317-Ab-2;
GM-Tg-bovg-MP0317-Ab-1/ GM-Tg-bovg-MP0317-Ab-2; GM-Tg-equg-MP0317-Ab-1/ GM-Tg-equg-MP0317-Ab-2
Products NameAnti-CNTN5 monoclonal antibody
Formatmab
Target NameCNTN5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CNTN5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CNTN5/ HNB-2s/ NB-2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0317
    Target NameCNTN5
    Gene ID53942,244682,114589,700826,485109,101099397,538198,100061138
    Gene Symbol and Synonyms6720426O10Rik,A830025P08Rik,CNTN5,Gm507,HNB-2s,NB-2
    Uniprot AccessionO94779,P97527
    Uniprot Entry NameCNTN5_HUMAN,CNTN5_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseLung Cancer
    Gene EnsemblENSG00000149972
    Target ClassificationN/A

    The target: CNTN5, gene name: CNTN5, also named as HNB-2s, NB-2. The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.