Anti-CDCP1/ CD318/ SIMA135 monoclonal antibody

Anti-CDCP1/ CD318/ SIMA135 antibody for FACS & in-vivo assay

Target products collectionGo to CDCP1/CDCP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0223-Ab-1/ GM-Tg-hg-MP0223-Ab-2Anti-Human CDCP1 monoclonal antibodyHuman
GM-Tg-rg-MP0223-Ab-1/ GM-Tg-rg-MP0223-Ab-2Anti-Rat CDCP1 monoclonal antibodyRat
GM-Tg-mg-MP0223-Ab-1/ GM-Tg-mg-MP0223-Ab-2Anti-Mouse CDCP1 monoclonal antibodyMouse
GM-Tg-cynog-MP0223-Ab-1/ GM-Tg-cynog-MP0223-Ab-2Anti-Cynomolgus/ Rhesus macaque CDCP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0223-Ab-1/ GM-Tg-felg-MP0223-Ab-2Anti-Feline CDCP1 monoclonal antibodyFeline
GM-Tg-cang-MP0223-Ab-1/ GM-Tg-cang-MP0223-Ab-2Anti-Canine CDCP1 monoclonal antibodyCanine
GM-Tg-bovg-MP0223-Ab-1/ GM-Tg-bovg-MP0223-Ab-2Anti-Bovine CDCP1 monoclonal antibodyBovine
GM-Tg-equg-MP0223-Ab-1/ GM-Tg-equg-MP0223-Ab-2Anti-Equine CDCP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0223-Ab-1/ GM-Tg-hg-MP0223-Ab-2; GM-Tg-rg-MP0223-Ab-1/ GM-Tg-rg-MP0223-Ab-2;
GM-Tg-mg-MP0223-Ab-1/ GM-Tg-mg-MP0223-Ab-2; GM-Tg-cynog-MP0223-Ab-1/ GM-Tg-cynog-MP0223-Ab-2;
GM-Tg-felg-MP0223-Ab-1/ GM-Tg-felg-MP0223-Ab-2; GM-Tg-cang-MP0223-Ab-1/ GM-Tg-cang-MP0223-Ab-2;
GM-Tg-bovg-MP0223-Ab-1/ GM-Tg-bovg-MP0223-Ab-2; GM-Tg-equg-MP0223-Ab-1/ GM-Tg-equg-MP0223-Ab-2
Products NameAnti-CDCP1 monoclonal antibody
Formatmab
Target NameCDCP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CDCP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CDCP1/ CD318/ SIMA135 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0223
    Target NameCDCP1
    Gene ID64866,109332,301082,714333,484797,101092249,540622,100065703
    Gene Symbol and Synonyms9030022E12Rik,CD318,CDCP1,E030027H19Rik,RGD1305578,SIMA135,TRASK
    Uniprot AccessionQ9H5V8
    Uniprot Entry NameCDCP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000163814
    Target ClassificationN/A

    The target: CDCP1, gene name: CDCP1, also named as CD318, SIMA135, TRASK. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.