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Anti-C1QR1/ CD93/ C1qR(P) monoclonal antibody
Anti-C1QR1/ CD93/ C1qR(P) antibody for FACS & in-vivo assay
Go to CD93/CD93 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0220-Ab-1/ GM-Tg-hg-MP0220-Ab-2 | Anti-Human CD93 monoclonal antibody | Human |
| GM-Tg-rg-MP0220-Ab-1/ GM-Tg-rg-MP0220-Ab-2 | Anti-Rat CD93 monoclonal antibody | Rat |
| GM-Tg-mg-MP0220-Ab-1/ GM-Tg-mg-MP0220-Ab-2 | Anti-Mouse CD93 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0220-Ab-1/ GM-Tg-cynog-MP0220-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CD93 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0220-Ab-1/ GM-Tg-felg-MP0220-Ab-2 | Anti-Feline CD93 monoclonal antibody | Feline |
| GM-Tg-cang-MP0220-Ab-1/ GM-Tg-cang-MP0220-Ab-2 | Anti-Canine CD93 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0220-Ab-1/ GM-Tg-bovg-MP0220-Ab-2 | Anti-Bovine CD93 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0220-Ab-1/ GM-Tg-equg-MP0220-Ab-2 | Anti-Equine CD93 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0220-Ab-1/ GM-Tg-hg-MP0220-Ab-2; GM-Tg-rg-MP0220-Ab-1/ GM-Tg-rg-MP0220-Ab-2; GM-Tg-mg-MP0220-Ab-1/ GM-Tg-mg-MP0220-Ab-2; GM-Tg-cynog-MP0220-Ab-1/ GM-Tg-cynog-MP0220-Ab-2; GM-Tg-felg-MP0220-Ab-1/ GM-Tg-felg-MP0220-Ab-2; GM-Tg-cang-MP0220-Ab-1/ GM-Tg-cang-MP0220-Ab-2; GM-Tg-bovg-MP0220-Ab-1/ GM-Tg-bovg-MP0220-Ab-2; GM-Tg-equg-MP0220-Ab-1/ GM-Tg-equg-MP0220-Ab-2 |
| Products Name | Anti-CD93 monoclonal antibody |
| Format | mab |
| Target Name | CD93 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CD93 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species C1QR1/ CD93/ C1qR(P) VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm004434 | mouse Cd93 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004434 | mouse Cd93 Lentivirus particle |
Target information
| Target ID | GM-MP0220 |
| Target Name | CD93 |
| Gene ID | 22918,17064,84398,702252,606923,101086798,539690,100059201 |
| Gene Symbol and Synonyms | 6030404G09Rik,AA4.1,C1qR(P),C1QR1,C1qRP,CD93,CDw93,dJ737E23.1,ECSM3,Ly68,MXRA4 |
| Uniprot Accession | Q9NPY3,Q9ET61 |
| Uniprot Entry Name | C1QR1_HUMAN,C1QR1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000125810 |
| Target Classification | N/A |
The target: CD93, gene name: CD93, also named as C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1. The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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