Anti-BT1A1/ BTN1A1/ BT monoclonal antibody

Anti-BT1A1/ BTN1A1/ BT antibody for FACS & in-vivo assay

Target products collectionGo to BTN1A1/BTN1A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0143-Ab-1/ GM-Tg-hg-MP0143-Ab-2Anti-Human BTN1A1 monoclonal antibodyHuman
GM-Tg-rg-MP0143-Ab-1/ GM-Tg-rg-MP0143-Ab-2Anti-Rat BTN1A1 monoclonal antibodyRat
GM-Tg-mg-MP0143-Ab-1/ GM-Tg-mg-MP0143-Ab-2Anti-Mouse BTN1A1 monoclonal antibodyMouse
GM-Tg-cynog-MP0143-Ab-1/ GM-Tg-cynog-MP0143-Ab-2Anti-Cynomolgus/ Rhesus macaque BTN1A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0143-Ab-1/ GM-Tg-felg-MP0143-Ab-2Anti-Feline BTN1A1 monoclonal antibodyFeline
GM-Tg-cang-MP0143-Ab-1/ GM-Tg-cang-MP0143-Ab-2Anti-Canine BTN1A1 monoclonal antibodyCanine
GM-Tg-bovg-MP0143-Ab-1/ GM-Tg-bovg-MP0143-Ab-2Anti-Bovine BTN1A1 monoclonal antibodyBovine
GM-Tg-equg-MP0143-Ab-1/ GM-Tg-equg-MP0143-Ab-2Anti-Equine BTN1A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0143-Ab-1/ GM-Tg-hg-MP0143-Ab-2; GM-Tg-rg-MP0143-Ab-1/ GM-Tg-rg-MP0143-Ab-2;
GM-Tg-mg-MP0143-Ab-1/ GM-Tg-mg-MP0143-Ab-2; GM-Tg-cynog-MP0143-Ab-1/ GM-Tg-cynog-MP0143-Ab-2;
GM-Tg-felg-MP0143-Ab-1/ GM-Tg-felg-MP0143-Ab-2; GM-Tg-cang-MP0143-Ab-1/ GM-Tg-cang-MP0143-Ab-2;
GM-Tg-bovg-MP0143-Ab-1/ GM-Tg-bovg-MP0143-Ab-2; GM-Tg-equg-MP0143-Ab-1/ GM-Tg-equg-MP0143-Ab-2
Products NameAnti-BTN1A1 monoclonal antibody
Formatmab
Target NameBTN1A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-BTN1A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species BT1A1/ BTN1A1/ BT VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0143
    Target NameBTN1A1
    Gene ID696,12231,306956,700608,100855656,101085974,282157,100065802
    Gene Symbol and SynonymsBT,BTN,BTN1,BTN1A1
    Uniprot AccessionQ13410,P18892
    Uniprot Entry NameBT1A1_HUMAN,BT1A1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000124557
    Target ClassificationN/A

    The target: BTN1A1, gene name: BTN1A1, also named as BT, BTN, BTN1. Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.