Anti-RIOK2 monoclonal antibody

Pre-made anti-RIOK2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RIOK2/RIOK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2708-Ab-1/ GM-Tg-hg-IP2708-Ab-2Anti-Human RIOK2 monoclonal antibodyHuman
GM-Tg-rg-IP2708-Ab-1/ GM-Tg-rg-IP2708-Ab-2Anti-Rat RIOK2 monoclonal antibodyRat
GM-Tg-mg-IP2708-Ab-1/ GM-Tg-mg-IP2708-Ab-2Anti-Mouse RIOK2 monoclonal antibodyMouse
GM-Tg-cynog-IP2708-Ab-1/ GM-Tg-cynog-IP2708-Ab-2Anti-Cynomolgus/ Rhesus macaque RIOK2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2708-Ab-1/ GM-Tg-felg-IP2708-Ab-2Anti-Feline RIOK2 monoclonal antibodyFeline
GM-Tg-cang-IP2708-Ab-1/ GM-Tg-cang-IP2708-Ab-2Anti-Canine RIOK2 monoclonal antibodyCanine
GM-Tg-bovg-IP2708-Ab-1/ GM-Tg-bovg-IP2708-Ab-2Anti-Bovine RIOK2 monoclonal antibodyBovine
GM-Tg-equg-IP2708-Ab-1/ GM-Tg-equg-IP2708-Ab-2Anti-Equine RIOK2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2708-Ab-1/ GM-Tg-hg-IP2708-Ab-2; GM-Tg-rg-IP2708-Ab-1/ GM-Tg-rg-IP2708-Ab-2;
GM-Tg-mg-IP2708-Ab-1/ GM-Tg-mg-IP2708-Ab-2; GM-Tg-cynog-IP2708-Ab-1/ GM-Tg-cynog-IP2708-Ab-2;
GM-Tg-felg-IP2708-Ab-1/ GM-Tg-felg-IP2708-Ab-2; GM-Tg-cang-IP2708-Ab-1/ GM-Tg-cang-IP2708-Ab-2;
GM-Tg-bovg-IP2708-Ab-1/ GM-Tg-bovg-IP2708-Ab-2; GM-Tg-equg-IP2708-Ab-1/ GM-Tg-equg-IP2708-Ab-2
Products NameAnti-RIOK2 monoclonal antibody
Formatmab
Target NameRIOK2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RIOK2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2708-Ag-1Recombinant multi-species RIOK2/ RIO2 protein


    Target information

    Target IDGM-IP2708
    Target NameRIOK2
    Gene ID55781,67045,308201,700738,479147,101083569,540772,100064864
    Gene Symbol and Synonyms2010110K24Rik,2410085M17Rik,RIO2,RIOK2
    Uniprot AccessionQ9BVS4
    Uniprot Entry NameRIOK2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000058729
    Target ClassificationKinase

    The target: RIOK2, gene name: RIOK2, also named as RIO2. Predicted to enable protein kinase activity. Involved in several processes, including positive regulation of rRNA processing; positive regulation of ribosomal small subunit export from nucleus; and regulation of mitotic metaphase/anaphase transition. Located in cytoplasm. Part of preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.