Anti-RC3H1 monoclonal antibody

Pre-made anti-RC3H1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RC3H1/RC3H1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2695-Ab-1/ GM-Tg-hg-IP2695-Ab-2Anti-Human RC3H1 monoclonal antibodyHuman
GM-Tg-rg-IP2695-Ab-1/ GM-Tg-rg-IP2695-Ab-2Anti-Rat RC3H1 monoclonal antibodyRat
GM-Tg-mg-IP2695-Ab-1/ GM-Tg-mg-IP2695-Ab-2Anti-Mouse RC3H1 monoclonal antibodyMouse
GM-Tg-cynog-IP2695-Ab-1/ GM-Tg-cynog-IP2695-Ab-2Anti-Cynomolgus/ Rhesus macaque RC3H1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2695-Ab-1/ GM-Tg-felg-IP2695-Ab-2Anti-Feline RC3H1 monoclonal antibodyFeline
GM-Tg-cang-IP2695-Ab-1/ GM-Tg-cang-IP2695-Ab-2Anti-Canine RC3H1 monoclonal antibodyCanine
GM-Tg-bovg-IP2695-Ab-1/ GM-Tg-bovg-IP2695-Ab-2Anti-Bovine RC3H1 monoclonal antibodyBovine
GM-Tg-equg-IP2695-Ab-1/ GM-Tg-equg-IP2695-Ab-2Anti-Equine RC3H1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2695-Ab-1/ GM-Tg-hg-IP2695-Ab-2; GM-Tg-rg-IP2695-Ab-1/ GM-Tg-rg-IP2695-Ab-2;
GM-Tg-mg-IP2695-Ab-1/ GM-Tg-mg-IP2695-Ab-2; GM-Tg-cynog-IP2695-Ab-1/ GM-Tg-cynog-IP2695-Ab-2;
GM-Tg-felg-IP2695-Ab-1/ GM-Tg-felg-IP2695-Ab-2; GM-Tg-cang-IP2695-Ab-1/ GM-Tg-cang-IP2695-Ab-2;
GM-Tg-bovg-IP2695-Ab-1/ GM-Tg-bovg-IP2695-Ab-2; GM-Tg-equg-IP2695-Ab-1/ GM-Tg-equg-IP2695-Ab-2
Products NameAnti-RC3H1 monoclonal antibody
Formatmab
Target NameRC3H1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RC3H1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2695-Ag-1Recombinant multi-species RC3H1/ RNF198/ ROQUIN protein


    Target information

    Target IDGM-IP2695
    Target NameRC3H1
    Gene ID149041,381305,680586,707745,480065,101096868,100336754,100052499
    Gene Symbol and Synonyms5730557L09Rik,FHL6,Gm551,IMDSHY,mKIAA2025,RC3H1,RGD1563512,RNF198,ROQUIN
    Uniprot AccessionQ5TC82
    Uniprot Entry NameRC3H1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000135870
    Target ClassificationN/A

    The target: RC3H1, gene name: RC3H1, also named as RNF198, ROQUIN. This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.