Anti-FABP3 monoclonal antibody

Pre-made anti-FABP3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FABP3/FABP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2483-Ab-1/ GM-Tg-hg-IP2483-Ab-2Anti-Human FABP3 monoclonal antibodyHuman
GM-Tg-rg-IP2483-Ab-1/ GM-Tg-rg-IP2483-Ab-2Anti-Rat FABP3 monoclonal antibodyRat
GM-Tg-mg-IP2483-Ab-1/ GM-Tg-mg-IP2483-Ab-2Anti-Mouse FABP3 monoclonal antibodyMouse
GM-Tg-cynog-IP2483-Ab-1/ GM-Tg-cynog-IP2483-Ab-2Anti-Cynomolgus/ Rhesus macaque FABP3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2483-Ab-1/ GM-Tg-felg-IP2483-Ab-2Anti-Feline FABP3 monoclonal antibodyFeline
GM-Tg-cang-IP2483-Ab-1/ GM-Tg-cang-IP2483-Ab-2Anti-Canine FABP3 monoclonal antibodyCanine
GM-Tg-bovg-IP2483-Ab-1/ GM-Tg-bovg-IP2483-Ab-2Anti-Bovine FABP3 monoclonal antibodyBovine
GM-Tg-equg-IP2483-Ab-1/ GM-Tg-equg-IP2483-Ab-2Anti-Equine FABP3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2483-Ab-1/ GM-Tg-hg-IP2483-Ab-2; GM-Tg-rg-IP2483-Ab-1/ GM-Tg-rg-IP2483-Ab-2;
GM-Tg-mg-IP2483-Ab-1/ GM-Tg-mg-IP2483-Ab-2; GM-Tg-cynog-IP2483-Ab-1/ GM-Tg-cynog-IP2483-Ab-2;
GM-Tg-felg-IP2483-Ab-1/ GM-Tg-felg-IP2483-Ab-2; GM-Tg-cang-IP2483-Ab-1/ GM-Tg-cang-IP2483-Ab-2;
GM-Tg-bovg-IP2483-Ab-1/ GM-Tg-bovg-IP2483-Ab-2; GM-Tg-equg-IP2483-Ab-1/ GM-Tg-equg-IP2483-Ab-2
Products NameAnti-FABP3 monoclonal antibody
Formatmab
Target NameFABP3
Protein Sub-locationIntrocelluar Protein
Category of antibodyDiagnostic target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FABP3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2483-Ag-1Recombinant multi-species FABPH/ FABP3/ FABP11 protein
    ORF Viral VectorvGMLP004884human FABP3 Lentivirus particle
    ORF Viral VectorpGMLP004884human FABP3 Lentivirus plasmid
    ORF Viral VectorpGMLPm004187mouse Fabp3 Lentivirus plasmid
    ORF Viral VectorvGMLPm004187mouse Fabp3 Lentivirus particle


    Target information

    Target IDGM-IP2483
    Target NameFABP3
    Gene ID2170,14077,79131,717237,478156,101093788,281758,100033895
    Gene Symbol and SynonymsFABP,FABP-3,FABP11,FABP3,Fabph-1,Fabph-4,Fabph1,Fabph4,H-FABP,M-FABP,MDGI,O-FABP
    Uniprot AccessionP05413,P07483,P10790
    Uniprot Entry NameFABPH_HUMAN,FABPH_RAT,FABPH_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryDiagnostics Biomarker
    DiseaseDiabetic Nephropathy, Autosomal Dominant Polycystic Kidney Disease, Proteinuria
    Gene EnsemblENSG00000121769
    Target ClassificationN/A

    The target: FABP3, gene name: FABP3, also named as FABP11, H-FABP, M-FABP, MDGI, O-FABP. The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.