Anti-FABP3 monoclonal antibody
Pre-made anti-FABP3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2483-Ab-1/ GM-Tg-hg-IP2483-Ab-2 | Anti-Human FABP3 monoclonal antibody | Human |
GM-Tg-rg-IP2483-Ab-1/ GM-Tg-rg-IP2483-Ab-2 | Anti-Rat FABP3 monoclonal antibody | Rat |
GM-Tg-mg-IP2483-Ab-1/ GM-Tg-mg-IP2483-Ab-2 | Anti-Mouse FABP3 monoclonal antibody | Mouse |
GM-Tg-cynog-IP2483-Ab-1/ GM-Tg-cynog-IP2483-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FABP3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2483-Ab-1/ GM-Tg-felg-IP2483-Ab-2 | Anti-Feline FABP3 monoclonal antibody | Feline |
GM-Tg-cang-IP2483-Ab-1/ GM-Tg-cang-IP2483-Ab-2 | Anti-Canine FABP3 monoclonal antibody | Canine |
GM-Tg-bovg-IP2483-Ab-1/ GM-Tg-bovg-IP2483-Ab-2 | Anti-Bovine FABP3 monoclonal antibody | Bovine |
GM-Tg-equg-IP2483-Ab-1/ GM-Tg-equg-IP2483-Ab-2 | Anti-Equine FABP3 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP2483-Ab-1/ GM-Tg-hg-IP2483-Ab-2; GM-Tg-rg-IP2483-Ab-1/ GM-Tg-rg-IP2483-Ab-2; GM-Tg-mg-IP2483-Ab-1/ GM-Tg-mg-IP2483-Ab-2; GM-Tg-cynog-IP2483-Ab-1/ GM-Tg-cynog-IP2483-Ab-2; GM-Tg-felg-IP2483-Ab-1/ GM-Tg-felg-IP2483-Ab-2; GM-Tg-cang-IP2483-Ab-1/ GM-Tg-cang-IP2483-Ab-2; GM-Tg-bovg-IP2483-Ab-1/ GM-Tg-bovg-IP2483-Ab-2; GM-Tg-equg-IP2483-Ab-1/ GM-Tg-equg-IP2483-Ab-2 |
Products Name | Anti-FABP3 monoclonal antibody |
Format | mab |
Target Name | FABP3 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Diagnostic target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-FABP3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP2483-Ag-1 | Recombinant multi-species FABPH/ FABP3/ FABP11 protein |
ORF Viral Vector | vGMLP004884 | human FABP3 Lentivirus particle |
ORF Viral Vector | pGMLP004884 | human FABP3 Lentivirus plasmid |
ORF Viral Vector | pGMLPm004187 | mouse Fabp3 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004187 | mouse Fabp3 Lentivirus particle |
Target information
Target ID | GM-IP2483 |
Target Name | FABP3 |
Gene ID | 2170,14077,79131,717237,478156,101093788,281758,100033895 |
Gene Symbol and Synonyms | FABP,FABP-3,FABP11,FABP3,Fabph-1,Fabph-4,Fabph1,Fabph4,H-FABP,M-FABP,MDGI,O-FABP |
Uniprot Accession | P05413,P07483,P10790 |
Uniprot Entry Name | FABPH_HUMAN,FABPH_RAT,FABPH_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Diagnostics Biomarker |
Disease | Diabetic Nephropathy, Autosomal Dominant Polycystic Kidney Disease, Proteinuria |
Gene Ensembl | ENSG00000121769 |
Target Classification | N/A |
The target: FABP3, gene name: FABP3, also named as FABP11, H-FABP, M-FABP, MDGI, O-FABP. The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.