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Anti-ABI1 monoclonal antibody
Pre-made anti-ABI1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ABI1/ABI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2328-Ab-1/ GM-Tg-hg-IP2328-Ab-2 | Anti-Human ABI1 monoclonal antibody | Human |
| GM-Tg-rg-IP2328-Ab-1/ GM-Tg-rg-IP2328-Ab-2 | Anti-Rat ABI1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2328-Ab-1/ GM-Tg-mg-IP2328-Ab-2 | Anti-Mouse ABI1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2328-Ab-1/ GM-Tg-cynog-IP2328-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ABI1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2328-Ab-1/ GM-Tg-felg-IP2328-Ab-2 | Anti-Feline ABI1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2328-Ab-1/ GM-Tg-cang-IP2328-Ab-2 | Anti-Canine ABI1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2328-Ab-1/ GM-Tg-bovg-IP2328-Ab-2 | Anti-Bovine ABI1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2328-Ab-1/ GM-Tg-equg-IP2328-Ab-2 | Anti-Equine ABI1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2328-Ab-1/ GM-Tg-hg-IP2328-Ab-2; GM-Tg-rg-IP2328-Ab-1/ GM-Tg-rg-IP2328-Ab-2; GM-Tg-mg-IP2328-Ab-1/ GM-Tg-mg-IP2328-Ab-2; GM-Tg-cynog-IP2328-Ab-1/ GM-Tg-cynog-IP2328-Ab-2; GM-Tg-felg-IP2328-Ab-1/ GM-Tg-felg-IP2328-Ab-2; GM-Tg-cang-IP2328-Ab-1/ GM-Tg-cang-IP2328-Ab-2; GM-Tg-bovg-IP2328-Ab-1/ GM-Tg-bovg-IP2328-Ab-2; GM-Tg-equg-IP2328-Ab-1/ GM-Tg-equg-IP2328-Ab-2 |
| Products Name | Anti-ABI1 monoclonal antibody |
| Format | mab |
| Target Name | ABI1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ABI1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2328-Ag-1 | Recombinant multi-species ABI1/ ABI-1/ ABLBP4 protein |
| ORF Viral Vector | pGMLV000850 | human ABI1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000850 | human ABI1 Lentivirus particle |
| ORF Viral Vector | pGMLP001443 | human ABI1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000849 | human ABI1 Lentivirus particle |
| ORF Viral Vector | vGMLP001443 | human ABI1 Lentivirus particle |
| ORF Viral Vector | pGMLV000849 | human ABI1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003965 | mouse Abi1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003965 | mouse Abi1 Lentivirus particle |
Target information
| Target ID | GM-IP2328 |
| Target Name | ABI1 |
| Gene ID | 10006,11308,79249,707698,607247,101082922,540815,100055377 |
| Gene Symbol and Synonyms | ABI-1,ABI1,ABLBP4,E3B1,NAP1,NAP1BP,SSH3BP,SSH3BP1 |
| Uniprot Accession | Q8IZP0,Q9QZM5 |
| Uniprot Entry Name | ABI1_HUMAN,ABI1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000136754 |
| Target Classification | N/A |
The target: ABI1, gene name: ABI1, also named as ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1. This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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