Anti-PLXNB2 monoclonal antibody

Pre-made anti-PLXNB2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PLXNB2/PLXNB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1418-Ab-1/ GM-Tg-hg-IP1418-Ab-2Anti-Human PLXNB2 monoclonal antibodyHuman
GM-Tg-rg-IP1418-Ab-1/ GM-Tg-rg-IP1418-Ab-2Anti-Rat PLXNB2 monoclonal antibodyRat
GM-Tg-mg-IP1418-Ab-1/ GM-Tg-mg-IP1418-Ab-2Anti-Mouse PLXNB2 monoclonal antibodyMouse
GM-Tg-cynog-IP1418-Ab-1/ GM-Tg-cynog-IP1418-Ab-2Anti-Cynomolgus/ Rhesus macaque PLXNB2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1418-Ab-1/ GM-Tg-felg-IP1418-Ab-2Anti-Feline PLXNB2 monoclonal antibodyFeline
GM-Tg-cang-IP1418-Ab-1/ GM-Tg-cang-IP1418-Ab-2Anti-Canine PLXNB2 monoclonal antibodyCanine
GM-Tg-bovg-IP1418-Ab-1/ GM-Tg-bovg-IP1418-Ab-2Anti-Bovine PLXNB2 monoclonal antibodyBovine
GM-Tg-equg-IP1418-Ab-1/ GM-Tg-equg-IP1418-Ab-2Anti-Equine PLXNB2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1418-Ab-1/ GM-Tg-hg-IP1418-Ab-2; GM-Tg-rg-IP1418-Ab-1/ GM-Tg-rg-IP1418-Ab-2;
GM-Tg-mg-IP1418-Ab-1/ GM-Tg-mg-IP1418-Ab-2; GM-Tg-cynog-IP1418-Ab-1/ GM-Tg-cynog-IP1418-Ab-2;
GM-Tg-felg-IP1418-Ab-1/ GM-Tg-felg-IP1418-Ab-2; GM-Tg-cang-IP1418-Ab-1/ GM-Tg-cang-IP1418-Ab-2;
GM-Tg-bovg-IP1418-Ab-1/ GM-Tg-bovg-IP1418-Ab-2; GM-Tg-equg-IP1418-Ab-1/ GM-Tg-equg-IP1418-Ab-2
Products NameAnti-PLXNB2 monoclonal antibody
Formatmab
Target NamePLXNB2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PLXNB2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1418-Ag-1Recombinant multi-species PLXB2/ PLXNB2/ MM1 protein


    Target information

    Target IDGM-IP1418
    Target NamePLXNB2
    Gene ID23654,140570,315217,720646,474459,101099059,508175,100056317
    Gene Symbol and SynonymsDebt,dJ402G11.3,lncFAL,MM1,Nbla00445,PLEXB2,plexin-B2,PLXNB2
    Uniprot AccessionO15031
    Uniprot Entry NamePLXB2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196576
    Target ClassificationN/A

    The target: PLXNB2, gene name: PLXNB2, also named as MM1, Nbla00445, PLEXB2, dJ402G11.3. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.