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Anti-NOMO1 monoclonal antibody
Pre-made anti-NOMO1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NOMO1/NOMO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1275-Ab-1/ GM-Tg-hg-IP1275-Ab-2 | Anti-Human NOMO1 monoclonal antibody | Human |
| GM-Tg-rg-IP1275-Ab-1/ GM-Tg-rg-IP1275-Ab-2 | Anti-Rat NOMO1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1275-Ab-1/ GM-Tg-mg-IP1275-Ab-2 | Anti-Mouse NOMO1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1275-Ab-1/ GM-Tg-cynog-IP1275-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NOMO1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1275-Ab-1/ GM-Tg-felg-IP1275-Ab-2 | Anti-Feline NOMO1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1275-Ab-1/ GM-Tg-cang-IP1275-Ab-2 | Anti-Canine NOMO1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1275-Ab-1/ GM-Tg-bovg-IP1275-Ab-2 | Anti-Bovine NOMO1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1275-Ab-1/ GM-Tg-equg-IP1275-Ab-2 | Anti-Equine NOMO1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1275-Ab-1/ GM-Tg-hg-IP1275-Ab-2; GM-Tg-rg-IP1275-Ab-1/ GM-Tg-rg-IP1275-Ab-2; GM-Tg-mg-IP1275-Ab-1/ GM-Tg-mg-IP1275-Ab-2; GM-Tg-cynog-IP1275-Ab-1/ GM-Tg-cynog-IP1275-Ab-2; GM-Tg-felg-IP1275-Ab-1/ GM-Tg-felg-IP1275-Ab-2; GM-Tg-cang-IP1275-Ab-1/ GM-Tg-cang-IP1275-Ab-2; GM-Tg-bovg-IP1275-Ab-1/ GM-Tg-bovg-IP1275-Ab-2; GM-Tg-equg-IP1275-Ab-1/ GM-Tg-equg-IP1275-Ab-2 |
| Products Name | Anti-NOMO1 monoclonal antibody |
| Format | mab |
| Target Name | NOMO1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NOMO1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1275-Ag-1 | Recombinant multi-species NOMO1/ Nomo/ PM5 protein |
Target information
| Target ID | GM-IP1275 |
| Target Name | NOMO1 |
| Gene ID | 23420 |
| Gene Symbol and Synonyms | Nomo,NOMO1,PM5 |
| Uniprot Accession | Q15155 |
| Uniprot Entry Name | NOMO1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000103512 |
| Target Classification | N/A |
The target: NOMO1, gene name: NOMO1, also named as Nomo, PM5. This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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