Anti-NAT8 monoclonal antibody
Pre-made anti-NAT8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1235-Ab-1/ GM-Tg-hg-IP1235-Ab-2 | Anti-Human NAT8 monoclonal antibody | Human |
GM-Tg-rg-IP1235-Ab-1/ GM-Tg-rg-IP1235-Ab-2 | Anti-Rat NAT8 monoclonal antibody | Rat |
GM-Tg-mg-IP1235-Ab-1/ GM-Tg-mg-IP1235-Ab-2 | Anti-Mouse NAT8 monoclonal antibody | Mouse |
GM-Tg-cynog-IP1235-Ab-1/ GM-Tg-cynog-IP1235-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NAT8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1235-Ab-1/ GM-Tg-felg-IP1235-Ab-2 | Anti-Feline NAT8 monoclonal antibody | Feline |
GM-Tg-cang-IP1235-Ab-1/ GM-Tg-cang-IP1235-Ab-2 | Anti-Canine NAT8 monoclonal antibody | Canine |
GM-Tg-bovg-IP1235-Ab-1/ GM-Tg-bovg-IP1235-Ab-2 | Anti-Bovine NAT8 monoclonal antibody | Bovine |
GM-Tg-equg-IP1235-Ab-1/ GM-Tg-equg-IP1235-Ab-2 | Anti-Equine NAT8 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1235-Ab-1/ GM-Tg-hg-IP1235-Ab-2; GM-Tg-rg-IP1235-Ab-1/ GM-Tg-rg-IP1235-Ab-2; GM-Tg-mg-IP1235-Ab-1/ GM-Tg-mg-IP1235-Ab-2; GM-Tg-cynog-IP1235-Ab-1/ GM-Tg-cynog-IP1235-Ab-2; GM-Tg-felg-IP1235-Ab-1/ GM-Tg-felg-IP1235-Ab-2; GM-Tg-cang-IP1235-Ab-1/ GM-Tg-cang-IP1235-Ab-2; GM-Tg-bovg-IP1235-Ab-1/ GM-Tg-bovg-IP1235-Ab-2; GM-Tg-equg-IP1235-Ab-1/ GM-Tg-equg-IP1235-Ab-2 |
Products Name | Anti-NAT8 monoclonal antibody |
Format | mab |
Target Name | NAT8 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-NAT8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1235-Ag-1 | Recombinant multi-species NAT8/ ATase2/ CCNAT protein |
ORF Viral Vector | pGMLP002633 | human NAT8 Lentivirus plasmid |
ORF Viral Vector | vGMLP002633 | human NAT8 Lentivirus particle |
ORF Viral Vector | pGMLPm000803 | mouse Nat8 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000803 | mouse Nat8 Lentivirus particle |
Target information
Target ID | GM-IP1235 |
Target Name | NAT8 |
Gene ID | 9027,706820,100856478,101098621,101902604 |
Gene Symbol and Synonyms | ATase2,CCNAT,CML1,GLA,Hcml1,NAT8,NAT8B,TSC501,TSC510 |
Uniprot Accession | Q9UHE5 |
Uniprot Entry Name | NAT8_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000144035 |
Target Classification | N/A |
The target: NAT8, gene name: NAT8, also named as ATase2, CCNAT, CML1, GLA, Hcml1, TSC501, TSC510. This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.