- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-MEGF8 monoclonal antibody
Pre-made anti-MEGF8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MEGF8/MEGF8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1165-Ab-1/ GM-Tg-hg-IP1165-Ab-2 | Anti-Human MEGF8 monoclonal antibody | Human |
| GM-Tg-rg-IP1165-Ab-1/ GM-Tg-rg-IP1165-Ab-2 | Anti-Rat MEGF8 monoclonal antibody | Rat |
| GM-Tg-mg-IP1165-Ab-1/ GM-Tg-mg-IP1165-Ab-2 | Anti-Mouse MEGF8 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1165-Ab-1/ GM-Tg-cynog-IP1165-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MEGF8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1165-Ab-1/ GM-Tg-felg-IP1165-Ab-2 | Anti-Feline MEGF8 monoclonal antibody | Feline |
| GM-Tg-cang-IP1165-Ab-1/ GM-Tg-cang-IP1165-Ab-2 | Anti-Canine MEGF8 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1165-Ab-1/ GM-Tg-bovg-IP1165-Ab-2 | Anti-Bovine MEGF8 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1165-Ab-1/ GM-Tg-equg-IP1165-Ab-2 | Anti-Equine MEGF8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1165-Ab-1/ GM-Tg-hg-IP1165-Ab-2; GM-Tg-rg-IP1165-Ab-1/ GM-Tg-rg-IP1165-Ab-2; GM-Tg-mg-IP1165-Ab-1/ GM-Tg-mg-IP1165-Ab-2; GM-Tg-cynog-IP1165-Ab-1/ GM-Tg-cynog-IP1165-Ab-2; GM-Tg-felg-IP1165-Ab-1/ GM-Tg-felg-IP1165-Ab-2; GM-Tg-cang-IP1165-Ab-1/ GM-Tg-cang-IP1165-Ab-2; GM-Tg-bovg-IP1165-Ab-1/ GM-Tg-bovg-IP1165-Ab-2; GM-Tg-equg-IP1165-Ab-1/ GM-Tg-equg-IP1165-Ab-2 |
| Products Name | Anti-MEGF8 monoclonal antibody |
| Format | mab |
| Target Name | MEGF8 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MEGF8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1165-Ag-1 | Recombinant multi-species MEGF8/ C19orf49/ CRPT2 protein |
Target information
| Target ID | GM-IP1165 |
| Target Name | MEGF8 |
| Gene ID | 1954,269878,114029,709352,484474,101085511,615688,100146203 |
| Gene Symbol and Synonyms | b2b1702.2Clo,b2b1702Clo,b2b288Clo,C19orf49,CRPT2,EGFL4,m687Ddg,MEGF8,mKIAA0817,SBP1 |
| Uniprot Accession | Q7Z7M0,Q9QYP0 |
| Uniprot Entry Name | MEGF8_HUMAN,MEGF8_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000105429 |
| Target Classification | N/A |
The target: MEGF8, gene name: MEGF8, also named as C19orf49, CRPT2, EGFL4, SBP1. The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
