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Anti-HBS1L monoclonal antibody
Pre-made anti-HBS1L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HBS1L/HBS1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0956-Ab-1/ GM-Tg-hg-IP0956-Ab-2 | Anti-Human HBS1L monoclonal antibody | Human |
| GM-Tg-rg-IP0956-Ab-1/ GM-Tg-rg-IP0956-Ab-2 | Anti-Rat HBS1L monoclonal antibody | Rat |
| GM-Tg-mg-IP0956-Ab-1/ GM-Tg-mg-IP0956-Ab-2 | Anti-Mouse HBS1L monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0956-Ab-1/ GM-Tg-cynog-IP0956-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HBS1L monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0956-Ab-1/ GM-Tg-felg-IP0956-Ab-2 | Anti-Feline HBS1L monoclonal antibody | Feline |
| GM-Tg-cang-IP0956-Ab-1/ GM-Tg-cang-IP0956-Ab-2 | Anti-Canine HBS1L monoclonal antibody | Canine |
| GM-Tg-bovg-IP0956-Ab-1/ GM-Tg-bovg-IP0956-Ab-2 | Anti-Bovine HBS1L monoclonal antibody | Bovine |
| GM-Tg-equg-IP0956-Ab-1/ GM-Tg-equg-IP0956-Ab-2 | Anti-Equine HBS1L monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0956-Ab-1/ GM-Tg-hg-IP0956-Ab-2; GM-Tg-rg-IP0956-Ab-1/ GM-Tg-rg-IP0956-Ab-2; GM-Tg-mg-IP0956-Ab-1/ GM-Tg-mg-IP0956-Ab-2; GM-Tg-cynog-IP0956-Ab-1/ GM-Tg-cynog-IP0956-Ab-2; GM-Tg-felg-IP0956-Ab-1/ GM-Tg-felg-IP0956-Ab-2; GM-Tg-cang-IP0956-Ab-1/ GM-Tg-cang-IP0956-Ab-2; GM-Tg-bovg-IP0956-Ab-1/ GM-Tg-bovg-IP0956-Ab-2; GM-Tg-equg-IP0956-Ab-1/ GM-Tg-equg-IP0956-Ab-2 |
| Products Name | Anti-HBS1L monoclonal antibody |
| Format | mab |
| Target Name | HBS1L |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HBS1L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0956-Ag-1 | Recombinant multi-species HBS1L/ EF-1a/ ERFS protein |
Target information
| Target ID | GM-IP0956 |
| Target Name | HBS1L |
| Gene ID | 10767,56422,293408,706748,476211,101100135,541083,100073159 |
| Gene Symbol and Synonyms | 2810035F15Rik,EF-1a,eRF3c,ERFS,HBS1,HBS1L,HSPC276 |
| Uniprot Accession | Q9Y450,Q6AXM7,Q2KHZ2 |
| Uniprot Entry Name | HBS1L_HUMAN,HBS1L_RAT,HBS1L_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112339 |
| Target Classification | N/A |
The target: HBS1L, gene name: HBS1L, also named as EF-1a, ERFS, HBS1, HSPC276, eRF3c. This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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