Anti-GPR89B monoclonal antibody

Pre-made anti-GPR89B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GPR89B/GPR89B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0942-Ab-1/ GM-Tg-hg-IP0942-Ab-2Anti-Human GPR89B monoclonal antibodyHuman
GM-Tg-rg-IP0942-Ab-1/ GM-Tg-rg-IP0942-Ab-2Anti-Rat GPR89B monoclonal antibodyRat
GM-Tg-mg-IP0942-Ab-1/ GM-Tg-mg-IP0942-Ab-2Anti-Mouse GPR89B monoclonal antibodyMouse
GM-Tg-cynog-IP0942-Ab-1/ GM-Tg-cynog-IP0942-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR89B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0942-Ab-1/ GM-Tg-felg-IP0942-Ab-2Anti-Feline GPR89B monoclonal antibodyFeline
GM-Tg-cang-IP0942-Ab-1/ GM-Tg-cang-IP0942-Ab-2Anti-Canine GPR89B monoclonal antibodyCanine
GM-Tg-bovg-IP0942-Ab-1/ GM-Tg-bovg-IP0942-Ab-2Anti-Bovine GPR89B monoclonal antibodyBovine
GM-Tg-equg-IP0942-Ab-1/ GM-Tg-equg-IP0942-Ab-2Anti-Equine GPR89B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0942-Ab-1/ GM-Tg-hg-IP0942-Ab-2; GM-Tg-rg-IP0942-Ab-1/ GM-Tg-rg-IP0942-Ab-2;
GM-Tg-mg-IP0942-Ab-1/ GM-Tg-mg-IP0942-Ab-2; GM-Tg-cynog-IP0942-Ab-1/ GM-Tg-cynog-IP0942-Ab-2;
GM-Tg-felg-IP0942-Ab-1/ GM-Tg-felg-IP0942-Ab-2; GM-Tg-cang-IP0942-Ab-1/ GM-Tg-cang-IP0942-Ab-2;
GM-Tg-bovg-IP0942-Ab-1/ GM-Tg-bovg-IP0942-Ab-2; GM-Tg-equg-IP0942-Ab-1/ GM-Tg-equg-IP0942-Ab-2
Products NameAnti-GPR89B monoclonal antibody
Formatmab
Target NameGPR89B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GPR89B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0942-Ag-1Recombinant multi-species GPHRB/ GPR89B/ GPHR protein


    Target information

    Target IDGM-IP0942
    Target NameGPR89B
    Gene ID51463
    Gene Symbol and SynonymsGPHR,GPR89,GPR89B,GPR89C,LINC02804,SH120,UNQ192
    Uniprot AccessionP0CG08
    Uniprot Entry NameGPHRB_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000188092
    Target ClassificationIon Channel

    The target: GPR89B, gene name: GPR89B, also named as GPHR, GPR89, GPR89C, SH120, UNQ192. Enables voltage-gated anion channel activity. Involved in intracellular pH reduction. Located in Golgi cisterna membrane and Golgi-associated vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.