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Anti-GPR161 monoclonal antibody
Pre-made anti-GPR161 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GPR161/GPR161 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0937-Ab-1/ GM-Tg-hg-IP0937-Ab-2 | Anti-Human GPR161 monoclonal antibody | Human |
| GM-Tg-rg-IP0937-Ab-1/ GM-Tg-rg-IP0937-Ab-2 | Anti-Rat GPR161 monoclonal antibody | Rat |
| GM-Tg-mg-IP0937-Ab-1/ GM-Tg-mg-IP0937-Ab-2 | Anti-Mouse GPR161 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0937-Ab-1/ GM-Tg-cynog-IP0937-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GPR161 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0937-Ab-1/ GM-Tg-felg-IP0937-Ab-2 | Anti-Feline GPR161 monoclonal antibody | Feline |
| GM-Tg-cang-IP0937-Ab-1/ GM-Tg-cang-IP0937-Ab-2 | Anti-Canine GPR161 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0937-Ab-1/ GM-Tg-bovg-IP0937-Ab-2 | Anti-Bovine GPR161 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0937-Ab-1/ GM-Tg-equg-IP0937-Ab-2 | Anti-Equine GPR161 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0937-Ab-1/ GM-Tg-hg-IP0937-Ab-2; GM-Tg-rg-IP0937-Ab-1/ GM-Tg-rg-IP0937-Ab-2; GM-Tg-mg-IP0937-Ab-1/ GM-Tg-mg-IP0937-Ab-2; GM-Tg-cynog-IP0937-Ab-1/ GM-Tg-cynog-IP0937-Ab-2; GM-Tg-felg-IP0937-Ab-1/ GM-Tg-felg-IP0937-Ab-2; GM-Tg-cang-IP0937-Ab-1/ GM-Tg-cang-IP0937-Ab-2; GM-Tg-bovg-IP0937-Ab-1/ GM-Tg-bovg-IP0937-Ab-2; GM-Tg-equg-IP0937-Ab-1/ GM-Tg-equg-IP0937-Ab-2 |
| Products Name | Anti-GPR161 monoclonal antibody |
| Format | mab |
| Target Name | GPR161 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GPR161 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0937-Ag-1 | Recombinant multi-species GP161/ GPR161/ RE2 protein |
| ORF Viral Vector | pGMLV000353 | human GPR161 Lentivirus plasmid |
| ORF Viral Vector | pGMLP003154 | human GPR161 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003154 | human GPR161 Lentivirus particle |
| ORF Viral Vector | vGMLV000353 | human GPR161 Lentivirus particle |
Target information
| Target ID | GM-IP0937 |
| Target Name | GPR161 |
| Gene ID | 23432,240888,289180,698934,490358,101100357,768006,100051574 |
| Gene Symbol and Synonyms | Gm208,Gm208Gpr,GPR161,RE2,RGD1563245,vl |
| Uniprot Accession | Q8N6U8,Q2YDN1 |
| Uniprot Entry Name | GP161_HUMAN,GP161_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143147 |
| Target Classification | N/A |
The target: GPR161, gene name: GPR161, also named as RE2. The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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