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Anti-ATG9B monoclonal antibody
Pre-made anti-ATG9B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ATG9B/ATG9B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0379-Ab-1/ GM-Tg-hg-IP0379-Ab-2 | Anti-Human ATG9B monoclonal antibody | Human |
| GM-Tg-rg-IP0379-Ab-1/ GM-Tg-rg-IP0379-Ab-2 | Anti-Rat ATG9B monoclonal antibody | Rat |
| GM-Tg-mg-IP0379-Ab-1/ GM-Tg-mg-IP0379-Ab-2 | Anti-Mouse ATG9B monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0379-Ab-1/ GM-Tg-cynog-IP0379-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ATG9B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0379-Ab-1/ GM-Tg-felg-IP0379-Ab-2 | Anti-Feline ATG9B monoclonal antibody | Feline |
| GM-Tg-cang-IP0379-Ab-1/ GM-Tg-cang-IP0379-Ab-2 | Anti-Canine ATG9B monoclonal antibody | Canine |
| GM-Tg-bovg-IP0379-Ab-1/ GM-Tg-bovg-IP0379-Ab-2 | Anti-Bovine ATG9B monoclonal antibody | Bovine |
| GM-Tg-equg-IP0379-Ab-1/ GM-Tg-equg-IP0379-Ab-2 | Anti-Equine ATG9B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0379-Ab-1/ GM-Tg-hg-IP0379-Ab-2; GM-Tg-rg-IP0379-Ab-1/ GM-Tg-rg-IP0379-Ab-2; GM-Tg-mg-IP0379-Ab-1/ GM-Tg-mg-IP0379-Ab-2; GM-Tg-cynog-IP0379-Ab-1/ GM-Tg-cynog-IP0379-Ab-2; GM-Tg-felg-IP0379-Ab-1/ GM-Tg-felg-IP0379-Ab-2; GM-Tg-cang-IP0379-Ab-1/ GM-Tg-cang-IP0379-Ab-2; GM-Tg-bovg-IP0379-Ab-1/ GM-Tg-bovg-IP0379-Ab-2; GM-Tg-equg-IP0379-Ab-1/ GM-Tg-equg-IP0379-Ab-2 |
| Products Name | Anti-ATG9B monoclonal antibody |
| Format | mab |
| Target Name | ATG9B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ATG9B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0379-Ag-1 | Recombinant multi-species ATG9B/ APG9L2/ NOS3AS protein |
| ORF Viral Vector | pGMLV000336 | human ATG9B Lentivirus plasmid |
| ORF Viral Vector | pGMLV000490 | human ATG9B Lentivirus plasmid |
| ORF Viral Vector | vGMLV000490 | human ATG9B Lentivirus particle |
| ORF Viral Vector | vGMLV000336 | human ATG9B Lentivirus particle |
Target information
| Target ID | GM-IP0379 |
| Target Name | ATG9B |
| Gene ID | 285973,213948,499973,714284,482799,101096716,506862,100064027 |
| Gene Symbol and Synonyms | Apg912,APG9L2,Apgdc2,ATG9B,eONE,Gm574,NOS3AS,RGD1560887,SONE |
| Uniprot Accession | Q674R7 |
| Uniprot Entry Name | ATG9B_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000181652 |
| Target Classification | N/A |
The target: ATG9B, gene name: ATG9B, also named as APG9L2, NOS3AS, SONE. This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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