Anti-AQP12B monoclonal antibody

Pre-made anti-AQP12B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to AQP12B/AQP12B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0344-Ab-1/ GM-Tg-hg-IP0344-Ab-2Anti-Human AQP12B monoclonal antibodyHuman
GM-Tg-rg-IP0344-Ab-1/ GM-Tg-rg-IP0344-Ab-2Anti-Rat AQP12B monoclonal antibodyRat
GM-Tg-mg-IP0344-Ab-1/ GM-Tg-mg-IP0344-Ab-2Anti-Mouse AQP12B monoclonal antibodyMouse
GM-Tg-cynog-IP0344-Ab-1/ GM-Tg-cynog-IP0344-Ab-2Anti-Cynomolgus/ Rhesus macaque AQP12B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0344-Ab-1/ GM-Tg-felg-IP0344-Ab-2Anti-Feline AQP12B monoclonal antibodyFeline
GM-Tg-cang-IP0344-Ab-1/ GM-Tg-cang-IP0344-Ab-2Anti-Canine AQP12B monoclonal antibodyCanine
GM-Tg-bovg-IP0344-Ab-1/ GM-Tg-bovg-IP0344-Ab-2Anti-Bovine AQP12B monoclonal antibodyBovine
GM-Tg-equg-IP0344-Ab-1/ GM-Tg-equg-IP0344-Ab-2Anti-Equine AQP12B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0344-Ab-1/ GM-Tg-hg-IP0344-Ab-2; GM-Tg-rg-IP0344-Ab-1/ GM-Tg-rg-IP0344-Ab-2;
GM-Tg-mg-IP0344-Ab-1/ GM-Tg-mg-IP0344-Ab-2; GM-Tg-cynog-IP0344-Ab-1/ GM-Tg-cynog-IP0344-Ab-2;
GM-Tg-felg-IP0344-Ab-1/ GM-Tg-felg-IP0344-Ab-2; GM-Tg-cang-IP0344-Ab-1/ GM-Tg-cang-IP0344-Ab-2;
GM-Tg-bovg-IP0344-Ab-1/ GM-Tg-bovg-IP0344-Ab-2; GM-Tg-equg-IP0344-Ab-1/ GM-Tg-equg-IP0344-Ab-2
Products NameAnti-AQP12B monoclonal antibody
Formatmab
Target NameAQP12B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-AQP12B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0344-Ag-1Recombinant multi-species AQ12B/ AQP12B/ INSSA3 protein


    Target information

    Target IDGM-IP0344
    Target NameAQP12B
    Gene ID653437
    Gene Symbol and SynonymsAQP12,AQP12A,AQP12B,INSSA3
    Uniprot AccessionA6NM10
    Uniprot Entry NameAQ12B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185176
    Target ClassificationN/A

    The target: AQP12B, gene name: AQP12B, also named as INSSA3. Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.