Anti-ABCB10 monoclonal antibody

Pre-made anti-ABCB10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ABCB10/ABCB10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0276-Ab-1/ GM-Tg-hg-IP0276-Ab-2Anti-Human ABCB10 monoclonal antibodyHuman
GM-Tg-rg-IP0276-Ab-1/ GM-Tg-rg-IP0276-Ab-2Anti-Rat ABCB10 monoclonal antibodyRat
GM-Tg-mg-IP0276-Ab-1/ GM-Tg-mg-IP0276-Ab-2Anti-Mouse ABCB10 monoclonal antibodyMouse
GM-Tg-cynog-IP0276-Ab-1/ GM-Tg-cynog-IP0276-Ab-2Anti-Cynomolgus/ Rhesus macaque ABCB10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0276-Ab-1/ GM-Tg-felg-IP0276-Ab-2Anti-Feline ABCB10 monoclonal antibodyFeline
GM-Tg-cang-IP0276-Ab-1/ GM-Tg-cang-IP0276-Ab-2Anti-Canine ABCB10 monoclonal antibodyCanine
GM-Tg-bovg-IP0276-Ab-1/ GM-Tg-bovg-IP0276-Ab-2Anti-Bovine ABCB10 monoclonal antibodyBovine
GM-Tg-equg-IP0276-Ab-1/ GM-Tg-equg-IP0276-Ab-2Anti-Equine ABCB10 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0276-Ab-1/ GM-Tg-hg-IP0276-Ab-2; GM-Tg-rg-IP0276-Ab-1/ GM-Tg-rg-IP0276-Ab-2;
GM-Tg-mg-IP0276-Ab-1/ GM-Tg-mg-IP0276-Ab-2; GM-Tg-cynog-IP0276-Ab-1/ GM-Tg-cynog-IP0276-Ab-2;
GM-Tg-felg-IP0276-Ab-1/ GM-Tg-felg-IP0276-Ab-2; GM-Tg-cang-IP0276-Ab-1/ GM-Tg-cang-IP0276-Ab-2;
GM-Tg-bovg-IP0276-Ab-1/ GM-Tg-bovg-IP0276-Ab-2; GM-Tg-equg-IP0276-Ab-1/ GM-Tg-equg-IP0276-Ab-2
Products NameAnti-ABCB10 monoclonal antibody
Formatmab
Target NameABCB10
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ABCB10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0276-Ag-1Recombinant multi-species ABCBA/ ABCB10/ EST20237 protein


    Target information

    Target IDGM-IP0276
    Target NameABCB10
    Gene ID23456,56199,361439,574117,100682973,101095197,789800,100065938
    Gene Symbol and SynonymsAbc-me,ABCB10,Abcb12,EST20237,M-ABC2,MTABC2
    Uniprot AccessionQ9NRK6
    Uniprot Entry NameABCBA_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000135776
    Target ClassificationN/A

    The target: ABCB10, gene name: ABCB10, also named as EST20237, M-ABC2, MTABC2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.  ABC proteins transport various molecules across extra- and intra-cellular membranes.  ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).  This protein is a member of the MDR/TAP subfamily.  Members of the MDR/TAP subfamily are involved in multidrug resistance.  The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.