Anti-S™N1 monoclonal antibody

Pre-made anti-S™N1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to S™N1/S™N1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0228-Ab-1/ GM-Tg-hg-IP0228-Ab-2Anti-Human S™N1 monoclonal antibodyHuman
GM-Tg-rg-IP0228-Ab-1/ GM-Tg-rg-IP0228-Ab-2Anti-Rat S™N1 monoclonal antibodyRat
GM-Tg-mg-IP0228-Ab-1/ GM-Tg-mg-IP0228-Ab-2Anti-Mouse S™N1 monoclonal antibodyMouse
GM-Tg-cynog-IP0228-Ab-1/ GM-Tg-cynog-IP0228-Ab-2Anti-Cynomolgus/ Rhesus macaque S™N1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0228-Ab-1/ GM-Tg-felg-IP0228-Ab-2Anti-Feline S™N1 monoclonal antibodyFeline
GM-Tg-cang-IP0228-Ab-1/ GM-Tg-cang-IP0228-Ab-2Anti-Canine S™N1 monoclonal antibodyCanine
GM-Tg-bovg-IP0228-Ab-1/ GM-Tg-bovg-IP0228-Ab-2Anti-Bovine S™N1 monoclonal antibodyBovine
GM-Tg-equg-IP0228-Ab-1/ GM-Tg-equg-IP0228-Ab-2Anti-Equine S™N1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0228-Ab-1/ GM-Tg-hg-IP0228-Ab-2; GM-Tg-rg-IP0228-Ab-1/ GM-Tg-rg-IP0228-Ab-2;
GM-Tg-mg-IP0228-Ab-1/ GM-Tg-mg-IP0228-Ab-2; GM-Tg-cynog-IP0228-Ab-1/ GM-Tg-cynog-IP0228-Ab-2;
GM-Tg-felg-IP0228-Ab-1/ GM-Tg-felg-IP0228-Ab-2; GM-Tg-cang-IP0228-Ab-1/ GM-Tg-cang-IP0228-Ab-2;
GM-Tg-bovg-IP0228-Ab-1/ GM-Tg-bovg-IP0228-Ab-2; GM-Tg-equg-IP0228-Ab-1/ GM-Tg-equg-IP0228-Ab-2
Products NameAnti-S™N1 monoclonal antibody
Formatmab
Target NameS™N1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-S™N1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0228-Ag-1Recombinant multi-species S™N1/ C1orf215/ LAP18 protein
    ORF Viral VectorpGMLV000379human S™N1 Lentivirus plasmid
    ORF Viral VectorvGMAD000071human S™N1 Adenovirus particle
    ORF Viral VectorvGMLV000481human S™N1 Lentivirus particle
    ORF Viral VectorvGMLV000379human S™N1 Lentivirus particle
    ORF Viral VectorpGMLV000481human S™N1 Lentivirus plasmid
    ORF Viral VectorvGMAP000293Human S™N1 Adenovirus particle
    ORF Viral VectorpGMAP000293Human S™N1 Adenovirus plasmid
    ORF Viral VectorpGMAD000071human S™N1 Adenovirus plasmid
    ORF Viral VectorpGMLPm000212mouse Stmn1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000212mouse Stmn1 Lentivirus particle


    Target information

    Target IDGM-IP0228
    Target NameS™N1
    Gene ID3925,16765,29332,719733,478175,101082582,616317,100057411
    Gene Symbol and Synonyms19k,C1orf215,Lag,LAP18,OP18,P18,P19,Pig,PP17,Pp18,PP19,PR22,prosolin,SMN,S™N1
    Uniprot AccessionP16949,P13668,Q3T0C7
    Uniprot Entry NameS™N1_HUMAN,S™N1_RAT,S™N1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000117632
    Target ClassificationTumor-associated antigen (TAA)

    The target: S™N1, gene name: S™N1, also named as C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN. This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.