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Anti-PEBP1 monoclonal antibody
Pre-made anti-PEBP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PEBP1/PEBP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0144-Ab-1/ GM-Tg-hg-IP0144-Ab-2 | Anti-Human PEBP1 monoclonal antibody | Human |
| GM-Tg-rg-IP0144-Ab-1/ GM-Tg-rg-IP0144-Ab-2 | Anti-Rat PEBP1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0144-Ab-1/ GM-Tg-mg-IP0144-Ab-2 | Anti-Mouse PEBP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0144-Ab-1/ GM-Tg-cynog-IP0144-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PEBP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0144-Ab-1/ GM-Tg-felg-IP0144-Ab-2 | Anti-Feline PEBP1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0144-Ab-1/ GM-Tg-cang-IP0144-Ab-2 | Anti-Canine PEBP1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0144-Ab-1/ GM-Tg-bovg-IP0144-Ab-2 | Anti-Bovine PEBP1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0144-Ab-1/ GM-Tg-equg-IP0144-Ab-2 | Anti-Equine PEBP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0144-Ab-1/ GM-Tg-hg-IP0144-Ab-2; GM-Tg-rg-IP0144-Ab-1/ GM-Tg-rg-IP0144-Ab-2; GM-Tg-mg-IP0144-Ab-1/ GM-Tg-mg-IP0144-Ab-2; GM-Tg-cynog-IP0144-Ab-1/ GM-Tg-cynog-IP0144-Ab-2; GM-Tg-felg-IP0144-Ab-1/ GM-Tg-felg-IP0144-Ab-2; GM-Tg-cang-IP0144-Ab-1/ GM-Tg-cang-IP0144-Ab-2; GM-Tg-bovg-IP0144-Ab-1/ GM-Tg-bovg-IP0144-Ab-2; GM-Tg-equg-IP0144-Ab-1/ GM-Tg-equg-IP0144-Ab-2 |
| Products Name | Anti-PEBP1 monoclonal antibody |
| Format | mab |
| Target Name | PEBP1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PEBP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0144-Ag-1 | Recombinant multi-species PEBP1/ HCNP/ HCNPpp protein |
| ORF Viral Vector | pGMLV000282 | human PEBP1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000282 | human PEBP1 Lentivirus particle |
| ORF Viral Vector | pGMAD000294 | mouse Pebp1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000294 | mouse Pebp1 Adenovirus particle |
Target information
| Target ID | GM-IP0144 |
| Target Name | PEBP1 |
| Gene ID | 5037,23980,29542,694697,477501,101092796,431786,100051008 |
| Gene Symbol and Synonyms | HCNP,HCNPpp,HEL-210,HEL-S-34,HEL-S-96,PBP,Pbp1,Pbpr,PEBP,PEBP-1,PEBP1,RKIP |
| Uniprot Accession | P30086,P31044,Q3YIX4,P13696 |
| Uniprot Entry Name | PEBP1_HUMAN,PEBP1_RAT,PEBP1_CANLF,PEBP1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Ovary Cancer, Ovarian cancer |
| Gene Ensembl | ENSG00000089220 |
| Target Classification | N/A |
The target: PEBP1, gene name: PEBP1, also named as HCNP, HCNPpp, HEL-210, HEL-S-34, HEL-S-96, PBP, PEBP, PEBP-1, RKIP. This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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