Anti-MAP4K1 monoclonal antibody

Pre-made anti-MAP4K1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MAP4K1/MAP4K1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0131-Ab-1/ GM-Tg-hg-IP0131-Ab-2Anti-Human MAP4K1 monoclonal antibodyHuman
GM-Tg-rg-IP0131-Ab-1/ GM-Tg-rg-IP0131-Ab-2Anti-Rat MAP4K1 monoclonal antibodyRat
GM-Tg-mg-IP0131-Ab-1/ GM-Tg-mg-IP0131-Ab-2Anti-Mouse MAP4K1 monoclonal antibodyMouse
GM-Tg-cynog-IP0131-Ab-1/ GM-Tg-cynog-IP0131-Ab-2Anti-Cynomolgus/ Rhesus macaque MAP4K1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0131-Ab-1/ GM-Tg-felg-IP0131-Ab-2Anti-Feline MAP4K1 monoclonal antibodyFeline
GM-Tg-cang-IP0131-Ab-1/ GM-Tg-cang-IP0131-Ab-2Anti-Canine MAP4K1 monoclonal antibodyCanine
GM-Tg-bovg-IP0131-Ab-1/ GM-Tg-bovg-IP0131-Ab-2Anti-Bovine MAP4K1 monoclonal antibodyBovine
GM-Tg-equg-IP0131-Ab-1/ GM-Tg-equg-IP0131-Ab-2Anti-Equine MAP4K1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0131-Ab-1/ GM-Tg-hg-IP0131-Ab-2; GM-Tg-rg-IP0131-Ab-1/ GM-Tg-rg-IP0131-Ab-2;
GM-Tg-mg-IP0131-Ab-1/ GM-Tg-mg-IP0131-Ab-2; GM-Tg-cynog-IP0131-Ab-1/ GM-Tg-cynog-IP0131-Ab-2;
GM-Tg-felg-IP0131-Ab-1/ GM-Tg-felg-IP0131-Ab-2; GM-Tg-cang-IP0131-Ab-1/ GM-Tg-cang-IP0131-Ab-2;
GM-Tg-bovg-IP0131-Ab-1/ GM-Tg-bovg-IP0131-Ab-2; GM-Tg-equg-IP0131-Ab-1/ GM-Tg-equg-IP0131-Ab-2
Products NameAnti-MAP4K1 monoclonal antibody
Formatmab
Target NameMAP4K1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MAP4K1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0131-Ag-1Recombinant multi-species M4K1/ MAP4K1/ HPK1 protein
    ORF Viral VectorvGMLV000175human MAP4K1 Lentivirus particle
    ORF Viral VectorpGMLV000175human MAP4K1 Lentivirus plasmid


    Target information

    Target IDGM-IP0131
    Target NameMAP4K1
    Gene ID11184,26411,292763,694259,484527,101101431,522002,100064279
    Gene Symbol and SynonymsHPK1,MAP4K1,mHPK1
    Uniprot AccessionQ92918
    Uniprot Entry NameM4K1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000104814
    Target ClassificationKinase

    The target: MAP4K1, gene name: MAP4K1, also named as HPK1. Enables ATP binding activity and MAP kinase kinase kinase kinase activity. Involved in several processes, including JNK cascade; cellular response to phorbol 13-acetate 12-myristate; and protein phosphorylation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.