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Anti-TSPO monoclonal antibody
Pre-made anti-TSPO monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TSPO/TSPO products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0017-Ab-1/ GM-Tg-hg-IP0017-Ab-2 | Anti-Human TSPO monoclonal antibody | Human |
| GM-Tg-rg-IP0017-Ab-1/ GM-Tg-rg-IP0017-Ab-2 | Anti-Rat TSPO monoclonal antibody | Rat |
| GM-Tg-mg-IP0017-Ab-1/ GM-Tg-mg-IP0017-Ab-2 | Anti-Mouse TSPO monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0017-Ab-1/ GM-Tg-cynog-IP0017-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TSPO monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0017-Ab-1/ GM-Tg-felg-IP0017-Ab-2 | Anti-Feline TSPO monoclonal antibody | Feline |
| GM-Tg-cang-IP0017-Ab-1/ GM-Tg-cang-IP0017-Ab-2 | Anti-Canine TSPO monoclonal antibody | Canine |
| GM-Tg-bovg-IP0017-Ab-1/ GM-Tg-bovg-IP0017-Ab-2 | Anti-Bovine TSPO monoclonal antibody | Bovine |
| GM-Tg-equg-IP0017-Ab-1/ GM-Tg-equg-IP0017-Ab-2 | Anti-Equine TSPO monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0017-Ab-1/ GM-Tg-hg-IP0017-Ab-2; GM-Tg-rg-IP0017-Ab-1/ GM-Tg-rg-IP0017-Ab-2; GM-Tg-mg-IP0017-Ab-1/ GM-Tg-mg-IP0017-Ab-2; GM-Tg-cynog-IP0017-Ab-1/ GM-Tg-cynog-IP0017-Ab-2; GM-Tg-felg-IP0017-Ab-1/ GM-Tg-felg-IP0017-Ab-2; GM-Tg-cang-IP0017-Ab-1/ GM-Tg-cang-IP0017-Ab-2; GM-Tg-bovg-IP0017-Ab-1/ GM-Tg-bovg-IP0017-Ab-2; GM-Tg-equg-IP0017-Ab-1/ GM-Tg-equg-IP0017-Ab-2 |
| Products Name | Anti-TSPO monoclonal antibody |
| Format | mab |
| Target Name | TSPO |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TSPO monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0017-Ag-1 | Recombinant multi-species TSPO/ TSPOB/ TSPO protein |
| ORF Viral Vector | pGMLP004600 | human TSPO Lentivirus plasmid |
| ORF Viral Vector | vGMLP004600 | human TSPO Lentivirus particle |
| ORF Viral Vector | pGMLPm000653 | mouse Tspo Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000653 | mouse Tspo Lentivirus particle |
Target information
| Target ID | GM-IP0017 |
| Target Name | TSPO |
| Gene ID | 706,12257,24230,711717,474475,101087076,281033,100071110 |
| Gene Symbol and Synonyms | BPBS,BZRP,DBI,IBP,MBR,mDRC,PBR,PBS,pk18,PKBS,PTBR,Ptbzr,PTBZR02,RATPTBZR02,TSPO,TSPO1 |
| Uniprot Accession | P30536, B1AH88,P16257,P30535 |
| Uniprot Entry Name | TSPOB_HUMAN,TSPO_RAT,TSPO_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000100300 |
| Target Classification | N/A |
The target: TSPO, gene name: TSPO, also named as BPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, mDRC, pk18. Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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