Anti-TRA monoclonal antibody
Pre-made anti-TRA monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-INN071-Ab-1/ GM-Tg-hg-INN071-Ab-2 | Anti-Human TRA monoclonal antibody | Human |
GM-Tg-rg-INN071-Ab-1/ GM-Tg-rg-INN071-Ab-2 | Anti-Rat TRA monoclonal antibody | Rat |
GM-Tg-mg-INN071-Ab-1/ GM-Tg-mg-INN071-Ab-2 | Anti-Mouse TRA monoclonal antibody | Mouse |
GM-Tg-cynog-INN071-Ab-1/ GM-Tg-cynog-INN071-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TRA monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-INN071-Ab-1/ GM-Tg-felg-INN071-Ab-2 | Anti-Feline TRA monoclonal antibody | Feline |
GM-Tg-cang-INN071-Ab-1/ GM-Tg-cang-INN071-Ab-2 | Anti-Canine TRA monoclonal antibody | Canine |
GM-Tg-bovg-INN071-Ab-1/ GM-Tg-bovg-INN071-Ab-2 | Anti-Bovine TRA monoclonal antibody | Bovine |
GM-Tg-equg-INN071-Ab-1/ GM-Tg-equg-INN071-Ab-2 | Anti-Equine TRA monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-INN071-Ab-1/ GM-Tg-hg-INN071-Ab-2; GM-Tg-rg-INN071-Ab-1/ GM-Tg-rg-INN071-Ab-2; GM-Tg-mg-INN071-Ab-1/ GM-Tg-mg-INN071-Ab-2; GM-Tg-cynog-INN071-Ab-1/ GM-Tg-cynog-INN071-Ab-2; GM-Tg-felg-INN071-Ab-1/ GM-Tg-felg-INN071-Ab-2; GM-Tg-cang-INN071-Ab-1/ GM-Tg-cang-INN071-Ab-2; GM-Tg-bovg-INN071-Ab-1/ GM-Tg-bovg-INN071-Ab-2; GM-Tg-equg-INN071-Ab-1/ GM-Tg-equg-INN071-Ab-2 |
Products Name | Anti-TRA monoclonal antibody |
Format | mab |
Target Name | TRA |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-TRA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Biosimilar | GMP-Bios-INN-906 | Pre-Made Maslimomab Biosimilar, Whole Mab: Anti-T Cell Receptor (Tr, Tr Alpha_Beta) [human] therapeutic antibody |
Target Antigen | GM-Tg-g-INN071-Ag-1 | Recombinant multi-species TRAR1/ TRAR2/ TRA protein |
Target information
Target ID | GM-INN071 |
Target Name | TRA |
Gene ID | 6955 |
Gene Symbol and Synonyms | IMD7,TCRA,TRA,TRA@ |
Uniprot Accession | P0DSE1, P0DTU3 |
Uniprot Entry Name | TRAR2_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target, INN Index |
Disease | Cancer |
Gene Ensembl | N/A |
Target Classification | Tumor-associated antigen (TAA) |
The target: TRA, gene name: TRA, also named as IMD7, TCRA, TCRD@, TRAC, TRA. Enables signaling receptor activity. Involved in T cell mediated cytotoxicity directed against tumor cell target and detection of tumor cell. Part of alpha-beta T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.