Human ERBB4/ALS19/HER4 ORF/cDNA clone-Lentivirus particle (NM_001042599.1)

Cat. No.: vGMLV000881

Pre-made Human ERBB4/ALS19/HER4 Lentiviral expression plasmid for ERBB4 lentivirus packaging, ERBB4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.

Target products collection

Go to Erbb-4/ERBB4/ALS19 products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdf MSDS
pdf Datasheet

Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLV000881 Human ERBB4 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLV000881
Gene Name ERBB4
Accession Number NM_001042599.1
Gene ID 2066
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 3879 bp
Gene Alias ALS19,HER4,p180erbB4
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T92057-Ab Anti-ERBB4/ Erbb-4/ ALS19 monoclonal antibody
    Target Antigen GM-Tg-g-T92057-Ag Erbb-4/ERBB4 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T92057 erb-b2 receptor tyrosine kinase 4 (ERBB4) protein & antibody
    ORF Viral Vector pGMLV000881 Human ERBB4 Lentivirus plasmid
    ORF Viral Vector pGMPC000626 Human ERBB4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000881 Human ERBB4 Lentivirus particle


    Target information

    Target ID GM-T92057
    Target Name Erbb-4
    Gene ID 2066, 13869, 693341, 59323, 101100073, 488508, 522419, 100050182
    Gene Symbol and Synonyms ALS19,c-erbB-4,ERBB4,HER4,p180erbB4
    Uniprot Accession Q15303
    Uniprot Entry Name ERBB4_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000178568
    Target Classification Tumor-associated antigen (TAA)

    This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.