Human PKP2/ARVD9 ORF/cDNA clone-Lentivirus particle (NM_001005242.2)
Pre-made Human PKP2/ARVD9 Lentiviral expression plasmid for PKP2 lentivirus packaging, PKP2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLV000468 | Human PKP2 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLV000468 |
Gene Name | PKP2 |
Accession Number | NM_001005242.2 |
Gene ID | 5318 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 2514 bp |
Gene Alias | ARVD9 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-MP2245-Ab | Anti-PKP2/ ARVD9 monoclonal antibody |
Target Antigen | GM-Tg-g-MP2245-Ag | PKP2 VLP (virus-like particle) |
ORF Viral Vector | pGMLV000468 | Human PKP2 Lentivirus plasmid |
ORF Viral Vector | vGMLV000468 | Human PKP2 Lentivirus particle |
Target information
Target ID | GM-MP2245 |
Target Name | PKP2 |
Gene ID | 5318, 67451, 100429378, 287925, 101091710, 486613, 537784, 100070065 |
Gene Symbol and Synonyms | 1200008D14Rik,1200012P04Rik,ARVD9,PKP2,Pkp2l |
Uniprot Accession | Q99959 |
Uniprot Entry Name | PKP2_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000057294 |
Target Classification | Not Available |
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene may regulate the signaling activity of beta-catenin and is required to maintain transcription of genes that control intracellular calcium cycling including ryanodine receptor 2, ankyrin-B, triadin, and calcium channel, voltage-dependent, L type, alpha 1C. Mutations in this gene are associated with different inherited cardiac conditions including Arrythmogenic Cardiomyopathy, Brugada Syndrome, and Idiopathic Ventricular Fibrillation. A processed pseudogene with high similarity to this gene has been mapped to chromosome 12p13. [provided by RefSeq, May 2022]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.