Human PLOD2/BRKS2/ LH2 ORF/cDNA clone-Lentivirus particle (NM_000935)
Pre-made Human PLOD2/BRKS2/ LH2 Lentiviral expression plasmid for PLOD2 lentivirus packaging, PLOD2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLV000439 | Human PLOD2 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLV000439 |
Gene Name | PLOD2 |
Accession Number | NM_000935 |
Gene ID | 5352 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 2214 bp |
Gene Alias | BRKS2, LH2, TLH |
Fluorescent Reporter | mCherry |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE0415-Ab | Anti-PLOD2/ BRKS2/ LH2 functional antibody |
Target Antigen | GM-Tg-g-SE0415-Ag | PLOD2 protein |
ORF Viral Vector | pGMLV000439 | Human PLOD2 Lentivirus plasmid |
ORF Viral Vector | vGMLV000439 | Human PLOD2 Lentivirus particle |
Target information
Target ID | GM-SE0415 |
Target Name | PLOD2 |
Gene ID | 5352, 26432, 715820, 300901, 101085741, 119865413, 533642, 100061030 |
Gene Symbol and Synonyms | BRKS2,D530025C14Rik,LH2,Plod-2,PLOD2,TLH |
Uniprot Accession | O00469 |
Uniprot Entry Name | PLOD2_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000152952 |
Target Classification | Not Available |
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.