Human PLOD2/BRKS2/LH2 ORF/cDNA clone-Lentivirus particle (NM_000935)

Cat. No.: vGMLV000439

Pre-made Human PLOD2/BRKS2/LH2 Lentiviral expression plasmid for PLOD2 lentivirus packaging, PLOD2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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pdf Datasheet

Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLV000439 Human PLOD2 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLV000439
Gene Name PLOD2
Accession Number NM_000935
Gene ID 5352
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 2214 bp
Gene Alias BRKS2,LH2,TLH
Fluorescent Reporter mCherry
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0415-Ab Anti-PLOD2/ BRKS2/ LH2 functional antibody
    Target Antigen GM-Tg-g-SE0415-Ag PLOD2 protein
    ORF Viral Vector pGMLV000439 Human PLOD2 Lentivirus plasmid
    ORF Viral Vector vGMLV000439 Human PLOD2 Lentivirus particle


    Target information

    Target ID GM-SE0415
    Target Name PLOD2
    Gene ID 5352, 26432, 715820, 300901, 101085741, 119865413, 533642, 100061030
    Gene Symbol and Synonyms BRKS2,D530025C14Rik,LH2,Plod-2,PLOD2,TLH
    Uniprot Accession O00469
    Uniprot Entry Name PLOD2_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000152952
    Target Classification Not Available

    The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.